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https://www.selleckchem.com/products/abt-199.html To investigate the prognostic value of serum amyloid A (SAA) in the patients with Corona Virus Disease 2019 (COVID-19). The medical data of 89 COVID-19 patients admitted to Renmin Hospital of Wuhan University from January 3, 2020 to February 26, 2020 were collected. Eighty-nine cases were divided into survival group (53 cases) and non-survival group (36 cases) according to the results of 28-day follow-up. The SAA levels of all patients were recorded and compared on 1day after admission (before treatment) and 3days, 5days, and 7days after treatment. The ROC curve was drawn to analyze the prognosis of patients with COVID-19 by SAA. The difference of comparison of SAA between survival group and non-survival group before treatment was not statistically significant, Z  = - 1.426, P = 0.154. The Z values (Z is the Z value of the rank sum test) of the two groups of patients at 3days, 5days, and 7days after treatment were - 5.569, - 6.967, and - 7.542, respectively. The P values were all less than 0.001, and the difference was statistically significant. The ROC curve results showed that SAA has higher sensitivity to the prognostic value of 1day (before treatment), 3days, 5days, and 7days after treatment, with values of 0.806, 0.972, 0.861, and 0.961, respectively. Compared with SAA on the 7th day and C-reactive protein, leukocyte count, neutrophil count, lymphocyte count, and hemoglobin on the 7th day, the sensitivities were 96.1%, 83.3%, 88.3%, 83.3%, 67.9%, and 83.0%, respectively, of which SAA has the highest sensitivity. SAA can be used as a predictor of the prognosis in patients with COVID-19. SAA can be used as a predictor of the prognosis in patients with COVID-19.In this paper, we propose an efficient computational method for converting local coordinates to world coordinates using specially structured coordinate data. The problem in question is the computation of world coordinates of an object throughout a motion, as

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