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https://www.selleckchem.com/products/caspofungin-acetate.html scRNA-seq identified five subpopulations of cells including closely related pericytes/vascular smooth muscle cells and three subpopulations of fibroblasts. All three fibroblast populations were PDGFRα+/CD34 + but were distinct in their expression of Ngfr/Spon2/Angptl7 (F1), Cxcl14/Smoc2/Rgs2 (F2), and Clec3b/Col14a1/Mmp3 (F3), with potential functions in the regulation of immune responses, response to wounding, and organization of extracellular matrix, respectively. Immunohistochemistry was used to investigate the spatial distribution of these populations revealing F1/NGFR + cells in most abundance beside epithelial cells. We provide the first definitive analysis of mesenchymal cells in the adult mouse endometrium identifying five subpopulations providing a platform for comparisons between mesenchymal cells in endometrium and other adult tissues which are prone to fibrosis.The disruption of mutualisms by invasive species has consequences for biodiversity loss and ecosystem function. Although invasive plant effects on the pollination of individual native species has been the subject of much study, their impacts on entire plant-pollinator communities are less understood. Community-level studies on plant invasion have mainly focused on two fronts understanding the mechanisms that mediate their integration; and their effects on plant-pollinator network structure. Here we briefly review current knowledge and propose a more unified framework for evaluating invasive species integration and their effects on plant-pollinator communities. We further outline gaps in our understanding and propose ways to advance knowledge in this field. Specifically, modeling approaches have so far yielded important predictions regarding the outcome and drivers of invasive species effects on plant communities. However, experimental studies that test these predictions in the field are lacking. We further emphasize the need to understa
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