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https://www.selleckchem.com/products/4-Methylumbelliferone(4-MU).html Fibrous carbon nanotubes (CNTs) and lamellar graphene oxide (GO) exhibit significant advantages for improving the fatigue properties of rubber composites. In this work, the synergistic effect of CNTs and GO on the modification of the microstructure and fatigue properties of natural rubber (NR) was comprehensively investigated. Results showed that CNTs and GO were interspersed, and they formed a strong filler network in the NR matrix. Compared with those of CNT/NR and GO/NR composites, the CNT-GO/NR composites showed the smallest crack precursor sizes, the lowest crack growth rates, more branching and deflections, and the longest fatigue life.Prospective studies and randomized controlled trials elucidating the impact of antioxidants supplementation on mortality risk are inconclusive. The present analysis determined association between regular antioxidants use and all-cause (primary objective), as well as cause-specific, mortality in 345,626 participants of the UK Biobank cohort using Cox proportional hazard models. All models were adjusted for confounders and multiple testing. Antioxidants users were defined as participants who indicated to regularly use at least one of the following multivitamins, vitamin C, vitamin E, selenium, and zinc. Median age of antioxidants users (n = 101,159) and non-users (n = 244,467) at baseline was 57 years. During 3.9 million person-years and a median follow-up of 11.5 years, 19,491 deaths occurred. Antioxidants use was not significantly associated with all-cause, cancer, and non-cancer mortality including several cancer and non-cancer subtypes. Interestingly, mortality risk from respiratory disease was significantly 21% lower among antioxidants users as compared to non-users (hazard ratio 0.79; 95% confidence interval 0.67, 0.92). In conclusion, the present study findings do not support recommendations for antioxidants supplementation to prevent all-cause, cancer, o

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