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https://www.selleckchem.com/products/Vorinostat-saha.html 264, p = 0.004), and heart rate (r = 0.275, p = 0.003) and negatively correlated with the hemoglobin level (r = -0.349, p less then 0.001). Multivariate regression analysis showed that the hemoglobin level (β = -0.254, tβ = -2.805, p = 0.006), BMI (β=0.240, t=2.770, p=0.007), and LVM (β=0.201, t=2.303, p=0.023) were independently associated with the frontal QRS-T angle. CONCLUSIONS The hemoglobin level was found to be an independent predictor of the frontal QRS-T angle.BACKGROUND Renal dysfunction, an important predictor of cardiovascular mortality, is paradoxically associated with a lower incidence of positive coronary fractional flow reserve (FFR) values, possibly due to renal disease-associated myocardial microvascular dysfunction. It is unknown if this relationship is influenced by arterial hypertension, a condition strongly associated with renal- and microvascular dysfunction. METHODS The incidence of positive ( less then 0.81) FFR values was retrospectively evaluated in consecutive patients with intermediate severity coronary artery lesions that were either associating or not associating renal dysfunction (creatinine clearance, CrCl less then 90ml/min/1.73m2), and had mild/moderate or severe arterial hypertension (treated by less then 3 or ≥3 different drugs). RESULTS Positive FFR values were found in 49.5% of the 109 included patients, with a significantly lower incidence in those with renal dysfunction 23 vs. 31 cases (39.7% vs. 60.8%, p=0.03). However, uni- and multivariate subpopulation analysis evidenced that renal dysfunction was a significant independent predictor of fewer positive FFR results only in severely hypertensive patients (univariate p values for mild/moderate and severe hypertension 0.80 and less then 0.01, respectively; multivariate p in severely hypertensive patients 0.04). This categorization significantly restricted the number of borderline FFR results (0.75- 0.80) where measuremen

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