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https://www.selleckchem.com/products/tefinostat.html The highly efficient detection of Salmonella typhimurium (S. typhimurium), a common foodborne bacterial, is important for the safety assurance of leafy vegetables. In this study, a fluorescent sensor (FMNCs-Apt), based on Fe3O4 magnetic nanoparticles and aptamer-modified carbon quantum dots, was developed for the rapid and highly sensitive detection of S. typhimurium in lettuce. First, carbon quantum dots were covalently bonded to the surface of prepared Fe3O4@chitosan to form magnetic fluorescence composite nanoparticles (FMNCs). Then, the aptamers of S. typhimurium were covalently linked to the surface (and named FMNCs-Apt). Fluorescence intensity of the FMNCs-Apt probes decreased as they aggregated on the surface of the bacteria, and the aggregation was separated using a magnet. Under the optimal conditions, the fluorescence change values of the solution showed a good linear relationship with the concentration of Salmonella (103-106 CFU mL-1). The detection limit of the method is 100 CFU mL-1 and 138 CFU mL-1 in fresh-cut vegetable washing solution and lettuce sample, respectively. Accordingly, this developed fluorescent probe became a highly sensitive and efficient sensor for the rapid detection of S. typhimurium in lettuce.Growth factors (GFs) have been well known for their therapeutic effects on wound healing. Due to their vulnerable biostability, biomaterial carriers are usually used to deliver GFs to maintain their bioactivity. Among the carriers, PEG hydrogels are the most widely applied. But the uncontrolled release of GFs and their immunogenicity dramatically retard the application of PEG hydrogels as carriers of GFs. Herein, FGF2 loaded zwitterionic sulfobetaine methacrylate (SBMA) hydrogels were developed, and it was revealed that these hydrogels were more effective in delivering FGF2 for wound healing than were PEG hydrogels. In vitro studies demonstrated that SBMA hydrogels could successfully prolon

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