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https://www.selleckchem.com/products/TW-37.html Collectively our data showed that BPA via GPER and/or EGFR transactivation induces activation of signal transduction pathways that mediate migration in TNBC MDA-MB-231 cells. Lichen sclerosus (LS) is an inflammatory dermatosis whose pathogenesis is incompletely understood. A retrospective review of patients with biopsy confirmed LS at University of Pittsburgh Medical Center (UPMC) clinical sites between 2009 and 2018 was conducted to study the link between breast cancer and LS. Out of 35 female patients who meet our inclusion criteria, 28.6% had a history of breast cancer, which is significantly higher than breast cancer prevalence (13%) in the United States. Interestingly, we have also observed a high rate of thyroid disease in patients with LS (32.6%), which is consistent with previous studies. Further studies are needed to delineate how breast cancer contributes to the development of LS, and whether screening for breast cancer has any utility in the management of LS. AIMS Although research exists on parental communication in adolescents with type 1 diabetes (T1D), the role of communication by health care providers remains understudied. Grounded in Self-Determination Theory, this study examined the role of autonomy-supportive communication (i.e., providing meaningful rationale and offering choices with regard to treatment recommendations) by providers and parents, and how they interact in the prediction of diabetes outcomes. METHODS In this cross-sectional study, 135 adolescents (mean age 14.3 ± 2.1SD years), 171 mothers, and 121 fathers reported on autonomy-supportive communication from health care providers and parents, and on adolescent treatment adherence. HbA1c values were retrieved from the medical record. RESULTS In adolescent reports, perceived autonomy-supportive communication from providers but not from parents was positively related to treatment adherence. A significant interaction between autonomy-support

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