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https://www.selleckchem.com/products/elamipretide-mtp-131.html The initial response to treatment, as assessed by CIBIC-Plus, remained stable for most outcome measures. Even small CIBIC-Plus improvement changes are associated with clinically meaningful change as assessed by GAS. Other tests detect decline better than improvement. We evaluated the short-term outcomes of robotic colorectal cancer surgery in octogenarian patients, focussing on postoperative morbidity and survival. All patients ≥80years in a prospective colorectal cancer database undergoing robotic curative colorectal cancer resection were included. Patient demographics, intraoperative findings, postoperative and oncological outcomes were recorded. Patients were further subdivided into two groups named old (OG80-85years) and very old (VOG≥86years). Fifty-eight consecutive patients were included (median age, 83years; male, 53.4%; median BMI, 26.5). Median total operative time was 230min, median blood loss 20ml, median length of stay 7days. Major complications were seen in 12% of patients; and the 90-day mortality rate was 1.7%. Complete R0 resection achieved in 93% of cases, average lymph node harvest was 22. Overall and disease-free survival was 81% and 87.3%, respectively (median follow-up 24.5months). We noticed a trend towards more advanced lesion staging in the VOG, but only N2 stage was significant (p=0.03). There was a statistically significant difference in overall survival in favour of the OG (p=0.024). Robotic surgery is feasible in octogenarian patients undergoing curative colorectal cancer resection and is associated with good post-operative outcomes and overall survival. Robotic surgery is feasible in octogenarian patients undergoing curative colorectal cancer resection and is associated with good post-operative outcomes and overall survival. To explore the different patterns of C-peptide decline in patients with and without partial remission of newly diagnosed type 1 diabetes (T1D). A total

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