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https://www.selleckchem.com/EGFR(HER).html 00; 95%CI 0.98-1.02). The overall rate of pathologic nodal upstaging was 19%. Modeled as a continuous variable, greater than 7 lymph nodes assessed at time of resection was significantly associated with nodal upstaging in multivariable regression (odds ratio [OR] 1.03; 95%CI 1.01-1.06). Conclusion In this study, there was no clear difference in survival based on increasing the number of lymph nodes assessed during lobectomy for limited stage SCLC. However, the number of retrieved lymph nodes was associated with pathologic nodal upstaging. Therefore, patients may benefit from retrieval of greater than 7 lymph nodes during lobectomy for SCLC.Background Serious Mental Illness (SMI), defined as a mental disorder causing functional impairment, affects 9.8 million Americans. SMI correlates with earlier onset, more extensive cardiac disease, and reduced life expectancy by 25 years. The impact of SMI on patients undergoing cardiac surgery has not been extensively studied. We hypothesized patients with SMI have worse cardiac surgery outcomes. Methods Using our institution's Society of Thoracic Surgeons database of 16,781 cardiac operations (2002-2017), a total of 1,445 patients (8.7%) were identified with SMI, and stratified into anxiety, mood disorders, and psychosis. The risk-adjusted impact on morbidity and mortality were evaluated using multivariable regression. Results Patients with SMI were more often female, younger, and had more comorbid disease. SMI patients were more likely to have had previous cardiac surgery and require urgent/emergent procedures (both p less then 0.05). Among specific SMI diagnoses, patients with psychosis had worse outcomes compared to the general population, with higher operative mortality (9.1% vs 4.2%, p=0.0001), major morbidity (30.4% vs 15.8%, p less then 0.0001), and cost ($50,211 vs $38,820, p less then 0.0001). After multivariable risk adjustment, SMI and psychosis remained independently associ

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