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https://www.selleckchem.com/products/ly2874455.html As a part of our ongoing investigations on passively fire protecting polymeric materials, we have been employing both reactive and additive routes involving phosphorus-containing compounds. These included inorganic and organic substances, and in the latter case, the phosphorus-bearing groups differed in terms of the chemical environments (phosphite, phosphate, phosphine, phosphine oxide and phosphonate ester) and oxidation state of the P atom (i.e., III, or V). The overall flammability profiles of wood substrates coated with the phosphorus-containing compounds were obtained through cone calorimetric measurements. The elemental composition, morphology and chemical natures of the char residues, obtained from the cone tests, were analysed through a variety of spectroscopic, chromatographic and spectrometric means. From the complementary information, obtained through these analyses, some probable mechanistic pathways that underpin the condensed- and gaseous-phase activities of the different additives are suggested. It was found that the inorganic solid additive, i.e., (NH4)2HPO4, underwent a two-step degradation, yielding ammonia gas and phosphoric acid. Furthermore, the liquid additives, owing to their volatility as compared to the solid ones, showed a relatively higher presence in the vapour phase than volatile fragments emanating from the latter ones (i.e., from phosphine and the phosphine oxides).Inner and middle ear disorders are the leading cause of hearing loss, and are said to be among the greatest risk factors of dementia. The use of regenerative medicine for the treatment of inner ear disorders may offer a potential alternative to cochlear implants for hearing recovery. In this paper, we reviewed recent research and clinical applications in middle and inner ear regeneration and cell therapy. Recently, the mechanism of inner ear regeneration has gradually been elucidated. "Inner ear stem cells," which may be c

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