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https://www.selleckchem.com/products/U0126.html Global sustainability is considered the number one health concern facing our planet. Dental care is currently not provided in a sustainable way. This study aims to quantify the potential environmental burden of an examination in a hypothetical dental practice and identify major contributors to environmental harm. A life cycle analysis was performed for the life cycle of an examination of one patient in a hypothetical dental practice. The equipment and products analysed were those available at the Faculty of Dentistry, Malmö University. The Ecoinvent version 3.5 database and the life cycle assessment software tool OpenLCA version 1.10 were chosen for this study. Normalized results indicate that the impact categories to which the modelled examination most significantly contributes are water scarcity, freshwater eutrophication and human toxicity (cancer effects). The major contributors or hotspots relating to the environmental harm of an examination procedure are soaps and detergents, disposable bibs, surfroducts used within dental care settings, potential trade-offs and dentistry's environmental burden. Oxaliplatin, a third-generation platinum derivative is commonly used in combination treatment of metastatic colorectal cancer. Since 2008, it is the second most common cause of drug-induced immune hemolytic anemia (DIIHA) investigated in our laboratory. Samples from fifteen patients including nine (60%) with intravascular hemolysis, suspected of having DIIHA were studied for the presence of anti-oxaliplatin. Direct antiglobulin tests (DATs) and tests with oxaliplatin-treated red blood cells (RBCs) or untreated and enzyme-treated RBCs in the presence of oxaliplatin were performed. A pool of normal AB sera with no unexpected antibodies was used as a control for nonimmunologic protein adsorption (NIPA). Eleven (73%) of the fifteen patients had antibodies to oxaliplatin that reacted with drug-treated RBCs and untreated RBCs i
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