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https://www.selleckchem.com/pd-1-pd-l1.html The odds ratios were used to measure associations. The review was performed among 11 studies of which 9 were cohort studies. The sample sizes ranged from 90 to 612 and comprised a total of 3,510 participants. The pooled prevalence of lost to follow-up was 8.66% (95% CI, 5.01-13.14) with a high heterogeneity (I2 = 93.49%, p<0.001). Pulmonary multi-drug resistant tuberculosis patients were 50% less likely to loss from follow-up compared to extra pulmonary tuberculosis patients. There was a high prevalence of lost to follow-up among multi-drug resistant tuberculosis patients in Ethiopia. Anatomical site of tuberculosis was a significant factor affecting lost to follow-up. Strengthening the health care system and patient education should be given a due emphasis. CRD42020153326; https//www.crd.york.ac.uk/prospero/display_record.php?RecordID=153326. CRD42020153326; https//www.crd.york.ac.uk/prospero/display_record.php?RecordID=153326.The purpose of the paper is to investigate spatial determinants of farmers' interest in pro-investment programs co-financed by the EU, by identifying and describing the territorial clusters of rural areas in Poland where the applications rates for these programs were above or below the national average. We tested for spatial autocorrelation using Moran's global spatial autocorrelation index, while the search for clusters was done using a local version of Moran's statistics. The results show significant regional variation in the farmers' interest in these programs in Poland. This interest was higher in regions with a greater level of agricultural development and better agrarian structure. In Poland, both of these factors are related not only to natural conditions, but also to strong historical context. We conclude that the pro-investment programs contribute to the deepening of development differences in Polish agriculture in the territorial dimension, which is not in line with the basic assumptions o

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