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https://www.selleckchem.com/products/--mk-801-maleate.html 0% versus 59.6%). Readmissions rates were lower for patients who were discharged with any form of ongoing medication assisted therapy compared to those who were not (30-day all cause readmissions 18.8% versus 35.1%; 30-day opioid-related readmissions 10.1% versus 29.9%; 90-day all-cause readmissions 27.3% versus 42.7%; 90-day opioid-related readmissions 15.1% versus 33.3%). Conclusions There is a strong association between medication assisted therapy and reduced against medical advice discharge rates. Additionally, maintenance medication assisted therapy at time of discharge is strongly associated with reduced readmissions rates.Objectives Current guidelines recommend pharmacologic prophylaxis for medical patients at high risk for venous thromboembolism. We aimed to assess the benefit and safety of venous thromboembolism prophylaxis in acutely ill medical patients hospitalized. Methods Retrospective cohort study in a tertiary hospital in Israel. Patients hospitalized in medical departments with an admission lasting more than 48 hours during 2014-2017. Primary outcome 30-day mortality. Secondary outcomes 90 day incidence of pulmonary embolism, symptomatic deep vein thrombosis, and major bleeding. Propensity-weighted logistic multivariate analysis was performed. Results A total of 18890 patient-unique episodes were included in the analysis. Of them 3206 (17.0%) received prophylaxis. A total of 1309 (6.9%) died, 540/3206 (16.8%) of those who received venous thromboembolism prophylaxis and 769/15864 (4.9%) of those who did not. Prophylaxis was not associated with a reduction in mortality, multivariable-adjusted odds ratio propensity-weighted (OR) 0.99 (95% confidence interval (CI) 0.84 - 1.14). 142 patients (0.7%) developed venous thromboembolism, 44/3206 (1.4%) of those who received prophylaxis and 98/15864 (0.6%) of those who did not. Prophylaxis was not associated with reduction in venous thromboembolism in t

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