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https://www.selleckchem.com/products/disodium-phosphate.html 5497, 0.5382, and 0.5911, respectively; however, the results of tremor, rigidity, and speech prediction were limited. Finally, accuracies of 76.92% were achieved in the UPDRS III improvement prediction. These findings confirmed that numerous left and right thalamic subnuclei were enlarged, accompanied by a few atrophies. The individual PD diagnosis, symptom, and clinical improvement prediction could be achieved based on morphology of thalamic subnuclei via machine learning. BACKGROUND The United States continues to experience an opioid epidemic of unprecedented proportions despite FDA approval of life saving medications, such as buprenorphine. This paper describes a novel group-based buprenorphine treatment model and summarizes patient characteristics and treatment retention. This model, known as the Comprehensive Opioid Addiction Treatment (COAT) program, was developed in West Virginia, the epicenter of the opioid epidemic. METHODS Data on 454 patients actively enrolled in the COAT program were extracted from an administrative clinical data set and electronic medical records and analyzed using descriptive and quantitative analysis to determine long-term retention in treatment using frequencies and means. RESULTS The characteristics of the 454 patients are as follows average age of 39, 53% female, predominantly white (94%) and Medicaid was the primary insurance provider (68%). Analysis of retention showed 37.8% of patents were retained less than one year and 14.7% were retained 10 or more years. Initiating treatment at a younger age was associated with long-term retention. CONCLUSION Opioid use disorder is a chronic relapsing disease and treatment models that retain patients long-term have the greatest benefit. The COAT model has been successful in retaining patients long-term in a rural setting where barriers to treatment are many. V.BACKGROUND Previous neuroimaging studies have revealed aberrant basal ga

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