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https://www.selleckchem.com/ 4% versus 25.0% and 41.0% versus 0%, respectively. The median postrelapse survival was 24.9 versus 13.5months, respectively. Pulmonary metastasectomy was independently associated with improved survival (hazard ratio, 0.185; 95% confidence interval, 0.103-0.330; P<.001). These results were confirmed by multiple propensity score analyses. Further stratified analysis revealed that the survival advantage associated with metastasectomy was not significant in patients with metastases involving ≥3 lung lobes and patients with very high pretreatment serum alkaline phosphatase (more than twice the upper limit). Pulmonary metastasectomy is associated with improved survival in patients with recurrent osteosarcoma. Pulmonary metastasectomy is associated with improved survival in patients with recurrent osteosarcoma. To report outcomes in a pilot study of autologous mitochondrial transplantation (MT) in pediatric patients requiring postcardiotomy extracorporeal membrane oxygenation (ECMO) for severe refractory cardiogenic shock after ischemia-reperfusion injury (IRI). A single-center retrospective study of patients requiring ECMO for postcardiotomy cardiogenic shock following IRI between May 2002 and December 2018 was performed. Postcardiotomy IRI was defined as coronary artery compromise followed by successful revascularization. Patients undergoing revascularization and subsequent MT were compared with those undergoing revascularization alone (Control). Twenty-four patients were included (MT, n=10; Control, n=14). Markers of systemic inflammatory response and organ function measured 1day before and 7days following revascularization did not differ between groups. Successful separation from ECMO-defined as freedom from ECMO reinstitution within 1week after initial separation-was possible for 8 patients in the MT grourol group (hazard ratio, 4.6; 95% confidence interval, 1.0 to 20.9; P = .04) CONCLUSIONS In this pilot study, MT was associated with succ
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