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https://www.selleckchem.com/TGF-beta.html The effect of various pretreatments on the bonding of a resin cement to resin-composite CAD/CAM blocks (RCBs) was examined. The surface of dispersed-filler RCBs (DF-RCBs) and a polymer infiltrated ceramic network RCB (PICN-RCB) was roughened using hydrofluoric acid etching (HF) or sandblasting, and followed by silanization and/or universal adhesive (UA) application. Microtensile bond strength (µTBS), surface roughness parameters (arithmetical mean height (Sa); developed interfacial area ratio (Sdr)), and critical surface energy (γc) were determined. For most DF-RCBs, the highest µTBS was obtained using HF+UA. UA application to DF-RCBs resulted in similar or higher µTBS compared to silanization, which indicates that silane treatment is not crucial for DF-RCBs, especially after HF. In contrast, the highest µTBS to PICN-RCB was obtained with silanization. Both roughening pretreatments significantly increased the surface roughness parameters and the γc of all RCBs. The γc was positively correlated with Sa (r=0.756, p less then 0.001) and Sdr (r=0.837, p less then 0.001).To investigate and analyze the impact of teeth preparation designs and sintering protocol on marginal fit and fracture resistance of monolithic translucent zirconia laminate veneers. A total of 40 extracted intact human maxillary central incisors were assigned into 4 groups (n=10/each group) to investigate 2 variables (1) the design of tooth preparation (a 1.5 mm incisal reduction with or without palatal chamfer) and (2) the two different sintering programs used for translucent zirconia restoration (standard or speed sintering procedure). Marginal discrepancy was evaluated using a digital microscope. The specimens were loaded to failure in the compression mode, using a universal testing machine with a crosshead speed of 0.5 mm/min. Marginal adaptation of monolithic translucent zirconia laminates are affected by both tooth preparation design and sintering protocol

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