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https://www.selleckchem.com/products/740-y-p-pdgfr-740y-p.html Quantifying robustness of farm animals is essential before it can be implemented in breeding and management strategies. A generic modelling and data analysis procedure was developed to quantify the feed intake response of growing pigs to perturbations in terms of resistance and resilience. The objective of this study was to apply this procedure to quantify these traits in 155 pigs from an experiment where they received diets with or without cereals contaminated with the mycotoxin deoxynivalenol (DON). The experimental pigs were divided equally in a control group and three DON-challenged groups. Pigs in each of the challenged groups received a diet contaminated with DON for 7 days early on (from 113 to 119 days of age), later on (from 134 to 140 days of age) or in both periods of the experiment. Results showed that the target feed intake trajectory of each pig could be estimated independently of the challenge. The procedure also estimated relatively accurately the times when DON was given to each challenged group. Results of the quantification of the feed intake response indicated that age and previous exposure to DON have an effect on the resilience capacity of the animals. The correlation between resistance and resilience traits was modest, indicating that these are different elements of robustness. The feed intake analysis procedure proved its capacity to detect and quantify the response of animals to perturbations, and the resulting response traits can potentially be used in breeding strategies.Tomasello frequently refers to joint commitment, but does not fully characterize it. In earlier publications, I have offered a detailed account of joint commitment, tying it to a sense that the parties form a "we," and arguing that it grounds directed obligations and rights. Here I outline my understanding of joint commitment and its normative impact.Bringing together the results of a large-scale review of Euro

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