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https://www.selleckchem.com/products/peg300.html 38, P = 0.020; r = -0.32, P = 0.052), tipping (r = -0.40, P = 0.015; r = -0.34, P = 0.034) and the antero-posterior direction (r = -0.31, P = 0.061; r = -0.36, P = 0.027); for the canines (right and left), as rotation around their long axis (r = -0.55, P = 0.003; r = -0.58, P = 0.002); for central incisors (right and left) in the antero-posterior direction (r = -0.55, P = 0.000; r = -0.48, P = 0.03), transverse direction (r = -0.43, P = 0.07; r = -0.32, P = 0.047), and rotation around their long axis (r = -0.53, P = 0.001; r = -0.28, P = 0.089). CONCLUSIONS Post-treatment changes in tooth position were mostly related to tooth movement during treatment. The reported correlations may help clinicians predict short-term relapse, evaluate long-term retention need, and design individualized retention schemes. © The Author(s) 2020. Published by Oxford University Press on behalf of the European Orthodontic Society. All rights reserved. For permissions, please email journals.permissions@oup.com.BACKGROUND Evaluating whether an infectious disease has reached a turning point is important for planning additional intervention efforts. This study aimed to analyze the changing patterns and the tempo-geographic features of the COVID-19 epidemic, to provide further evidence for real-time responses. METHODS Daily data on COVID-2019 cases between 31st Dec. 2019 and 26th Feb. 2020 were collected and analyzed for Hubei and non-Hubei regions. Observed trends for new and cumulative cases were analyzed through joint-point regressions. Spatial analysis was applied to show the geographic distribution and changing pattern of the epidemic. RESULTS By 26th Feb. 2020, 78,630 confirmed COVID-19 cases had been reported in China. In Hubei, an increasing trend (slope=221) was observed for new cases between 24th Jan. and February 7th Feb. 2020, after which a decline commenced (slope=-868). However, as the diagnosis criteria changed, a sudden increase (

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