Yam Code

New Paste Browse

https://pragmatickr.com/ Pragmatic Free Trial Meta Pragmatic Free Trial Meta is a non-commercial, open data platform and infrastructure that facilitates research on pragmatic trials. It collects and distributes clean trial data, ratings and evaluations using PRECIS-2. This allows for diverse meta-epidemiological analyses to evaluate the effects of treatment across trials of various levels of pragmatism. Background Pragmatic trials provide real-world evidence that can be used to make clinical decisions. The term "pragmatic" however, is a word that is often used in contradiction and its definition and evaluation need further clarification. Pragmatic trials are intended to guide clinical practices and policy decisions, not to verify a physiological hypothesis or clinical hypothesis. A pragmatic trial should aim to be as close as it is to the real-world clinical practice that include recruiting participants, setting, design, delivery and implementation of interventions, determining and analysis outcomes, and primary analyses. This is a significant difference between explanatory trials as defined by Schwartz and Lellouch1 which are designed to test the hypothesis in a more thorough way. Studies that are truly pragmatic should avoid attempting to blind participants or clinicians as this could result in bias in the estimation of the effects of treatment. Practical trials should also aim to enroll patients from a variety of health care settings, to ensure that their findings are generalizable to the real world. Additionally the focus of pragmatic trials should be on outcomes that are vital for patients, such as quality of life or functional recovery. This is particularly relevant in trials that require the use of invasive procedures or could have harmful adverse consequences. The CRASH trial29, for instance focused on the functional outcome to evaluate a two-page case report with an electronic system for the monitoring of hospitalized patients with chronic heart failure. Si

Paste Settings

Paste Title : [Optional]

Paste Folder : [Optional]

Syntax Highlighting : [Optional]

Paste Expiration : [Optional]

Paste Status : [Optional]

Password : [Optional]

Description: [Optional]

Tags: [Optional]

Encrypt Paste (?)

You are currently not logged in, this means you can not edit or delete anything you paste. Sign Up or Login

Paste Settings

Site Languages