https://www.selleckchem.com/products/Temsirolimus.html 2%) patients with at least one PSMA-FDG+ lesion. The prostate-specific antigen (PSA) and Gleason score were both higher in the patients with PSMA-FDG+ lesions than in those without PSMA-FDG+ lesions (P = 0.04 and P less then 0.001, respectively). Multivariate regression analysis showed that the Gleason score (≥8) and PSA (≥7.9 ng/mL) were associated with the detection rate of patients who had PSMA-FDG+ lesions (P = 0.01 and P = 0.04, respectively). The incidences of having PSMA-FDG+ lesions in low-probability (Gleason score less then 8 and PSA less then 7.9 ng/mL), medium-probability (Gleason score≥8 and PSA less then 7.9 ng/mL or Gleason score less then 8 and PSA≥7.9 ng/mL), and high-probability (Gleason score≥8 and PSA≥7.9 ng/mL) groups were 0%, 21.7%, and 61.5%, respectively (P less then 0.001). Conclusion Gleason score and PSA are significant predictors for PSMA-FDG+ lesions, and CRPC patients with high Gleason score and PSA may benefit from additional 18F-FDG PET/CT.With hundreds of millions of coronavirus disease 2019 (COVID-19) mRNA-based vaccine doses planned to be delivered worldwide in the upcoming months, it is important to recognize positron emission tomography with computed tomography (PET/CT) findings in recently vaccinated immunocompetent or immunocompromised patients. We aimed to assess PET/CT uptake in the deltoid muscle and axillary lymph nodes of patients that received a COVID-19 mRNA-based vaccine, and to evaluate its association with patients' age and immune status. Methods All consecutive adult subjects undergoing PET/CT scans with any radiotracer at our center during the first month of a national COVID-19 vaccination rollout (between 23 December 2020 and January 27, 2021) were included. Data regarding clinical status, laterality and time interval from recent COVID-19 mRNA vaccination was prospectively collected and retrospectively analyzed, and correlated with deltoid muscle and axillary l