https://www.selleckchem.com/products/relacorilant.html The potential of the evolving protocol is demonstrated with 4 representative case reports. Each case report demonstrates one level of the protocol. The protocol seems to be both feasible and effective for better clarification of the communication abilities of DOC patients. We recommend its continued evaluation employing a more structured study. IMPLICATIONS FOR REHABILITATION We suggest a systematic method for rehabilitation of patients with disorders of consciousness It is based upon monitoring patient engagement in real-time and selecting interventions accordingly. The protocol seems to be both feasible and effective for better clarification of the communication abilities of DOC patients. We recommend its continued evaluation employing a more structured study. IMPLICATIONS FOR REHABILITATION We suggest a systematic method for rehabilitation of patients with disorders of consciousness It is based upon monitoring patient engagement in real-time and selecting interventions accordingly. To evaluate the characteristics and response to therapy for HCC in sub-Saharan Africa. We retrospectively evaluated demographic, clinical and outcome variables of HCC in a referral clinic in Ethiopia from 2016 to 2018. Survival assessment was performed using the Mann-Whitney test. Associations between categorical variables was assessed using Pearson Chi-square test. We report 46 HCC cases with a median age of 54 years (IQR 45-62) and 50% female. Viral hepatitis was the most common underlying etiology, with 41% of subjects infected with hepatitis B virus (HBV) and 45% with hepatitis C. The median MELD was 12 (IQR 8-17), we found no association between survival and a MELD score </> 15, regardless of underlying disease (pr=0.61, p>0.05). 31% of individuals underwent supportive treatment with a median survival of 27 days (IQR 19-181), 18% used Sorafenib (median survival of 94 days, IQR 24-121), and trans-arterial chemoembolization (TAC