https://www.selleckchem.com/products/baricitinib-ly3009104.html up. There is moderate-certainty evidence that the Hydrus microstent is probably more effective than the iStent in lowering IOP of people with OAG in the short-term. Few studies were available on the effects of the Hydrus microstent, therefore the results of this review may not be applicable to all people with OAG, particularly in selected people with medically uncontrolled glaucoma, since IOP was controlled with medication in many participants in the included studies. Complications may be rare using the Hydrus microstent, as well as the comparator iStent, but larger studies are needed to investigate its safety. Copyright © 2020 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.The prognosis for patients with refractory cardiac arrest transferred to hospital during ongoing resuscitation is poor.1 Additionally in remote areas, the response time of the emergency medical services (EMS) may be long, which further decreases the likelihood of a good outcome. The most common reason for sudden death during cross-country skiing is acute coronary artery syndrome and subsequent ventricular fibrillation (VF). This article is protected by copyright. All rights reserved.BACKGROUND Warfarin is underutilised in frail older people because of the fear of bleeding complications. Drug interactions are an independent bleeding risk factor. However, the extent to which potential drug interactions are taken into account at warfarin therapy initiation in frail patients is not known. OBJECTIVE The objective of this study was to investigate the use of potentially interacting drugs increasing the bleeding risk before and after warfarin initiation in frail and non-frail patients. METHODS We conducted an observational study including inpatients aged ≥ 60 years initiated on warfarin in a tertiary hospital in Adelaide, South Australia. Frailty status was assessed with the Reported Edmonton Frail Scale. Medication charts w