OBJECTIVE In 1998, the Europe Region of the World Health Organization set the goal of eliminating measles. In this study, the prevalence of immunity against measles virus in the population of the health area of Santiago de Compostela was analyzed based on data obtained between 2008-2018. METHODS A total of 7,150 different patients were studied and divided into groups according to their year of birth 2010-2017, 2000-2009, 1990-1999, 1980-1989, 1953-1979 and less then 1953. The serum determination of IgG against measles virus was performed using a commercialized chemiluminescent immunoassay. RESULTS A minimum (76%) was observed for measles virus protection rates in those born between 1990-1999.  https://www.selleckchem.com/products/ulonivirine.html  By age group it was seen that in all groups the women presented a higher percentage of antibodies against measles. In a logistic regression model with year of birth and sex, an odds ratio of 1.06 (p less then 0.001) was obtained for the year of birth and of 0.82 (p=0.0013) for sex. CONCLUSIONS It was observed lower seroprevalences from the implantation of the vaccine and a more pronounced change during the implantation period. From the vaccination plan for measles of the year 2000 in Galicia, the rates of protection against the virus of the measles have been increasing in our area. Although there is a greater proportion of women protected against men, these differences are small. ©The Author 2020. Published by Sociedad Española de Quimioterapia. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)(https//creativecommons.org/licenses/by-nc/4.0/).BACKGROUND It is currently unknown if muscle growth and strength gain are similar in both dominant and non-dominant limbs of the same individual with the same training load. Therefore, the objective of this study was to analyze initial muscle size and strength levels in both upper limbs and compare changes in muscle size and strength between dominant and non-dominant upper limbs with a within-individual experimental design with high-load resistance training. METHODS Ten untrained participants performed six weeks of unilateral resistance training for upper limbs (i.e., elbow flexors) using 80% of 1 repetition maximum (1RM). Muscle thickness and 1RM were assessed before and after the training period. We used a two-way repeated measures ANOVA to compared changes between limbs, effect sizes (ES) were also calculated. RESULTS Muscle thickness and 1RM were not different between limbs at baseline. There was a main time effect for muscle thickness (p less then 0.0001; dominant 10 ± 4%, ES = 0.83; non-dominant 11 ± 3%, ES = 0.85) and 1RM (p less then 0.0001; dominant 23 ± 15%, ES = 1.8; non-dominant 30 ± 17%, ES = 1.9), but there was no interaction effect for muscle thickness (p = 0.63) and 1RM (p = 0.32). There was no difference between dominant and non-dominant limbs in volume load (ES = 0.4; p = 0.13). CONCLUSIONS Similar baseline strength level and muscle thickness, and training volume may explain similar adaptations observed. Within-individual design seems reliable to investigate training models as both limbs adapt similarly to the same stimulus.BACKGROUND Obesity is a multicausal illness that generates large expenses to health systems and also for the families of obese individuals. It is important to note that obesity disrupts all systems, generating metabolic consequences that may be irreversible. Interdisciplinary therapy is recommended as the primary method for treating obesity. However, the cost of interdisciplinary treatment can be high due to the need for various professionals, from different areas of expertise. This study compares the effects of 32 weeks of physical training combined with interdisciplinary therapy on anthropometric and biochemical parameters in obese women. METHODS 76 subjects were randomized into two groups Group Physical Exercise (EXE) and Group Interdisciplinary Treatment (INTER), being evaluated in the initial moment and after 32 weeks. 30 subjects completed the intervention and were evaluated (EXE n=13; INTER n=17). RESULTS Psychobiological and biochemical variables were measured. EXE and INTER were similar before treatment and both showed significantly improvements in anthropometric and biochemical parameters after interventions, without difference between groups. CONCLUSIONS The results confirmed the relevant role of physical training or the interdisciplinary therapy on metabolic profile of obese women. We realized that physical training can be incorporated into public or private health systems as an alternative strategy for obesity control, especially in locations that do not have the possibility of offering a complete interdisciplinary therapy.BACKGROUND Physical exercise plays an important role in bone mineralization as well as factors involved in bone metabolism influence the athletic performance. In European countries, soccer is the most popular sport. The aim of the study was to investigate bone metabolism, bone mass and structural integrity profile in professional male adult football players. METHODS Sixteen professional male football players from a single team of the 2nd division Italian League (mean age 22.4±0.7 years) were enrolled. Bone biochemical parameters, including serum calcium, phosphorus, albumin, creatinine, alkaline phosphatase, intact plasma PTH, 25-hydroxy- vitamin D (25-OHD), 24-h urinary calcium and phosphorus, and calcaneal quantitative ultrasound (QUS), were evaluated at the beginning (October 2012) and at the end of the League (May 2013). RESULTS 25-OHD levels were significantly lower at the end of the League compared to the beginning (27.1 ± 5.9 vs 36.6 ± 9.5 ng/ml, fold change (FC)=0.25, p=0.008), and the prevalence of 25-OHD deficiency increased from 25 to 73%. Moreover, higher rate of previous bone, cartilage or ligament injuries correlated with 25-OHD deficiencies (p=0.014). T-score and Z-score were at the upper limits of the normality ranges, without significant difference between the beginning and end of the League. Phosphaturia was slightly decreased at the end of the League [(691.0 ± 364.5 vs 934.0 ± 274.3 mg/24h, FC=0.26, p=0.06)]. A significant correlation was found between phosphaturia and BQI (R square=0.28, p=0.03), and both T-s and Z-s (R square=0.28, p=0.03) at the beginning of the League. CONCLUSIONS With this pilot study, we demonstrated that vitamin D status significantly worsened at the end of the League. Therefore, vitamin D supplementation might be suggested in adult football players in order to prevent vitamin D deficiency and improve the athletic performance.