https://www.iampsychiatry.uk/adhd-treatment-for-adults/ Adult ADHD and Comorbid Disorders Many people with ADHD also have comorbid disorders such as major depressive disorder (Kessler and colleagues 2006). Many people who suffer from depression are not able to respond well to medications and may get better results from therapy. Neurotransmitters are brain chemicals that regulate and increase levels of certain brain chemicals. The most frequently prescribed stimulants include methylphenidate, amphetamine and other similar medications. Medicines A variety of medications used to treat ADHD in children can also be used for adults. However the dosages differ and the medications can cause side effects that are not present in children. A doctor will look at the individual's medical history, family history and other health conditions to determine what medication is best for him or her. The most common type of ADHD medication is stimulant. It works by adjusting levels of two chemical messengers in the brain called norepinephrine and dopamine. as methylphenidate (also called Adderall) and dextroamphetamine increase the availability of neurotransmitters, which help improve focus, reduce impulsivity, and reduce aggression. They come in various forms such as chewable tablets, liquids and skin patches. Long-acting versions of these stimulants are preferred as they result in more patient compliance and lasting more smooth improvement in symptoms. It is crucial to remember that comorbid conditions like depression or anxiety disorders can influence the response to ADHD medication. Therefore, it is recommended that these psychiatric problems be treated first before medications be used as a secondary measure. The drugs that can be used for comorbidity disorders include atomoxetine (Bupropion) tricyclic antidepressants as well as bupropion (Wilens, 2004). Certain patients might experience a "rebound effect" where their ADHD symptoms worsen after discontinuing stimulant medications. In