https://www.selleckchem.com/btk.html This article describes the dataset for the elucidation of the possible mechanisms of antidiarrhoeal actions of methanol leaves extract of Combretum hypopilinum (Diels) Combretaceae in mice. The plant has been used in traditional medicine to treat diarrhoea in Nigeria and other African countries. We introduce the data for the antidiarrhoeal activity of the methanol leaf extract of Combretum hypopilinum at 1,000 mg/kg investigated using charcoal meal test in mice with loperamide (5 mg/kg) as the standard antidiarrhoeal agent. To elucidate the possible mechanisms of its antidiarrhoeal action, naloxone (2 mg/kg), prazosin (1 mg/kg), yohimbine (2 mg/kg), propranolol (1 mg/kg), pilocarpine (1 mg/kg) and isosorbide dinitrate (150 mg/kg) were separately administered to different groups of mice 30 minutes before administration of the extract. Each mouse was dissected using dissecting set, and the small intestine was immediately removed from pylorus to caecum, placed lengthwise on moist filter paper and measured the dicomputational-based and artificial intelligence approaches, including predictive modelling and simulation.This article provides data projections of replacement ratios of the pension income relative to the last labor earnings for the Chilean cohorts of retirees between 2015 and 2055. Time series are presented for the percentiles 1, 5, 10, 25, 50, 75, 90, 95 and 99 of each cohort to fully characterize the heterogeneity of the living standards during retirement over the entire period. The datasets are available in Excel and Stata. The dataset is useful for academics, policy makers and financial analysts to plot the impact of policies such as increasing the contribution rate or delaying the retirement age on the pension income of future retirees for each generation between 2015 and 2055. The dataset also shows the heterogeneous impact of those policies including statistics for the mean plus the percentiles 1, 5, 10, 25, 50, 75, 9