003). Seven of the 10 subjects with normal weight had GH increase above the threshold for GH sufficiency compared with only 2 subjects with overweight and obesity. Growth hormone response to the modified repeated WAnT was significantly reduced among children with overweight and obesity compared with those with normal weight. Anaerobic interval-type training may not be a sufficient exercise alternative to stimulate appropriate GH levels among children with obesity.Yepes, MM, Feliu, GM, Bishop, C, and Gonzalo-Skok, O. Assessing the reliability and validity of agility testing in team sports A systematic review. J Strength Cond Res XX(X) 000-000, 2020-The aims of this systematic review were to (a) examine the reliability of the reactive agility tests and (b) analyze the discriminatory validity of the agility tests. A literature search was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). We explored PubMed, SPORTDiscus, and Cochrane Plus databases looking for articles about agility in team sports. After filtering for article relevance, only 42 studies met the inclusion criteria; 37 of which assessed the reliability of agility tests and 22 assessing their validity. Reliability showed a high intraclass correlation coefficient (ICC) in almost all studies (range 0.79-0.99) with the exception of 2 studies. In addition, other studies also assessed the reliability of decision time (ICC = 0.95), movement time (ICC = 0.92), and decision accuracy (ICC = 0.74-0.93), all of which exhibited acceptable reliability. Furthermore, these data show high discriminatory validity, with higher performance level players being faster than lower performance level players (mean = 6.4%, range = 2.1-25.3%), with a faster decision time (mean = 23.2%, range = 10.2-48.0%) with the exception of 1 study, and better decision accuracy (mean = 9.3%, range = 2.5-21.0%). Thus, it can be concluded that reactive agility tests show good reliability and discriminatory validity. However, most agility tests occur in simple contexts whereby only 2 possible responses are possible. Therefore, future research should consider creating more specific and complex environments that challenge the cognitive process of high-level athletes.
  To assess the relationship between subjective cognitive symptoms and objective cognitive test scores in patients after concussion. We additionally examined factors associated with subjective and objective cognitive dysfunction, as well as their discrepancy.
 
  Eighty-six individuals (65.1% female; 74.4% adult) from an interdisciplinary concussion clinic.
 
  Subjective and objective cognitive functioning was measured via the SCAT-Symptom Evaluation and the CNS Vital Signs Neurocognition Index (NCI), respectively. Cognitive discrepancy scores were derived by calculating standardized residuals (via linear regression) using subjective symptoms as the outcome and NCI score as the predictor. Hierarchical regression assessed predictors (age, education, time postinjury, attention-deficit/hyperactivity disorder, affective distress, and sleep disturbance) of cognitive discrepancy scores. Nonparametric analyses evaluated relationships between predictor variables, subjective symptoms, and NCI.
 
  More severe affective and sleep symptoms (large and medium effects), less time postinjury (small effect), and older age (small effect) were associated with higher subjective cognitive symptoms. Higher levels of affective distress and less time since injury were associated with higher cognitive discrepancy scores (β = .723, P < .001; β = -.204, P < .05, respectively).
 
  Clinical interpretation of subjective cognitive dysfunction should consider these additional variables. Evaluation of affective distress is warranted in the context of higher subjective cognitive complaints than objective test performance.
 Clinical interpretation of subjective cognitive dysfunction should consider these additional variables. Evaluation of affective distress is warranted in the context of higher subjective cognitive complaints than objective test performance.
  The duration of the acute period of recovery following traumatic brain injury (TBI) remains a widely used criterion for injury severity and clinical management. Consensus regarding its most appropriate definition and assessment method has yet to be established.
 
  The present study compared the trajectory of recovery using 3 measures the Westmead Post-Traumatic Amnesia Scale (WPTAS), the Galveston Orientation and Amnesia Test (GOAT), and the Confusion Assessment Protocol (CAP). Patterns of symptom recovery using the CAP were explored.
 
  Eighty-two participants with moderate to severe TBI in posttraumatic amnesia (PTA) on admission to an inpatient rehabilitation hospital.
 
  Prospective longitudinal study.
 
  Length of PTA (days), agreement between measures (%, κ coefficient), and pattern of symptom recovery.
 
  Participants emerged from PTA earliest on the CAP followed the GOAT, and last on the WPTAS. There was good agreement between the CAP and the GOAT as to PTA status, but both tests had poor agreement with the WPTAS. Of patients considered out of PTA on the CAP, the majority exhibited signs of amnesia on the WPTAS and one-third had clinical levels of agitation.
 
  The WPTAS identifies a later stage of PTA recovery that requires specialized management due to ongoing amnesia and agitation.  https://www.selleckchem.com/products/triparanol-mer-29.html  The CAP and the GOAT are less sensitive to this extended period of PTA.
 The WPTAS identifies a later stage of PTA recovery that requires specialized management due to ongoing amnesia and agitation. The CAP and the GOAT are less sensitive to this extended period of PTA.
  This study examined the use of antipsychotics for managing agitation during posttraumatic amnesia (PTA) after traumatic brain injury (TBI) and its relationship with agitated behavior.
 
  Observational prospective study with correlational design.
 
  Inpatient rehabilitation hospital for TBI.
 
  A total of 125 consecutive admissions who were in PTA and had moderate-severe TBI.
 
  Antipsychotic use was compared with agitation levels as measured by the total scores on the Agitated Behavior Scale (ABS).
 
  Atypical antipsychotics were used in one-third of participants to manage agitation. Antipsychotic use was more common in participants with high levels of global agitation; however, there were many on antipsychotics who had mild or even no agitation according to the ABS. Uncontrolled observational data found no reduction in agitation after antipsychotic commencement or dose increase.
 
  Antipsychotics are commonly used to manage agitation after TBI despite limited evidence of efficacy. Agitation should be formally monitored in PTA to ensure antipsychotics are used to manage more severe agitation and for evaluating treatment response.