https://www.selleckchem.com/products/cm-4620.html To evaluate the clinical impact and technical feasibility of augmented reality laparoscopic navigation (ARLN) system in laparoscopic splenectomy for massive splenomegaly. The clinical data of 17 consecutive patients who underwent laparoscopic splenectomy using ARLN (ARLN group) and 26 patients without ARLN guidance (Non-ARLN group) between January 2018 and April 2020 were enrolled. Propensity score matching (PSM) analysis was performed between the patients with and without ARLN guidance at a ratio of 11. Mean intraoperative blood loss was significantly lower in the ARLN-group than in the Non-ARLN group (306.6ml vs. 462.6ml, p = 0.047). All the patients in the ARLN-group achieved successful splenic artery dissection, while surgical success was achieved in 12 patients in the Non-ARLN group (p = 0.044). Postoperative hospital stay was significantly longer in the Non-ARLN group (3.8days vs. 4.5days, p = 0.040). ARLN can provide feasible and accurate intraoperative image guidance, and it could be helpful in the performance of laparoscopic splenectomy for massive splenomegaly. ARLN can provide feasible and accurate intraoperative image guidance, and it could be helpful in the performance of laparoscopic splenectomy for massive splenomegaly. The present study investigated whether or not passive stretching increases the force-generating capacity of the antagonist muscle, and the possible neuromuscular mechanisms behind. To this purpose, the neuromuscular function accompanying the force-generating capacity was assessed in 26 healthy male volunteers after passive stretching and in a control session. Before and after passive intermittent static stretching of the plantar flexors consisting of five sets × 45s + 15s-rest, maximum voluntary isometric contraction (MVC) and surface electromyographic root mean square (sEMG RMS) were measured in the tibialis anterior (the antagonist muscle). Additionally, evoked V wave, H-reflex, and M