https://www.selleckchem.com/products/cx-4945-silmitasertib.html The current study aimed to verify the changes in performance, physiological and biomechanical variables throughout a season in master swimmers. Twenty-three master swimmers (34.9 ± 7.4 years) were assessed three times during a season (December M , March M , June M ), in indoor 25 m swimming pools. An incremental 5 × 200 m test was used to evaluate the speed at 4 mmol·L of blood lactate concentration (sLT), maximal oxygen uptake ( ), peak blood lactate ([La-]peak) after the test, stroke frequency ( ), stroke length ( ), stroke index ( ) and propelling efficiency ( ). The performance was assessed in the 200 m front crawl during competition. Swimming performance improved between M , M (2%, = 0.03), and M (4%, < 0.001). Both sLT and increased throughout the season (4% and 18%, < 0.001, respectively) but not [La-]peak. While decreased 5%, , and increased 5%, 7%, and 6% ( < 0.001) from M to M . Master swimmers improved significantly in their 200 m front crawl performance over a season, with decreased and increased and Despite the improvement in energetic variables, the change in performance seemed to be more dependent on technical than energetic factors. Master swimmers improved significantly in their 200 m front crawl performance over a season, with decreased SF, and increased SL, ηp and SI. Despite the improvement in energetic variables, the change in performance seemed to be more dependent on technical than energetic factors.Temporomandibular joint (TMJ) disorder has been reported to be 1.5 to two times more common in women than men. Such a gender-based difference could be attributed to behavioral, hormonal, anatomical, and psychological characteristics. Physiological hormonal differences between genders could be one of the possible explanations for the higher incidence of temporomandibular disorder (TMD) in women. As the plasma level of certain female hormones increases during gestation, it could be assum