https://www.selleckchem.com/products/ganetespib-sta-9090.html These findings can help explain why veterinarians are leaving the profession or reducing their work hours, as well as emphasize the importance of continuing education of veterinarians on self-care and coping with stress, help with resolving ethical dilemmas, and working as a team. The results give a deeper understanding of sources of stress and the difficulties experienced in coping. These findings can help explain why veterinarians are leaving the profession or reducing their work hours, as well as emphasize the importance of continuing education of veterinarians on self-care and coping with stress, help with resolving ethical dilemmas, and working as a team.Balloon cell melanoma (BCM) is a rare presentation of malignant melanoma characterized by large, foamy melanocytes lacking pigmentation. This is a comprehensive review of the clinical, dermoscopic, and histological features among BCM cases reported in the literature. A systematic review of all case reports and series published since 1970 was conducted via MEDLINE, Embase, and Web of Science, using "balloon cell melanoma" and synonymous search terms. Our systematic search identified 76 cases (49% male, 51% female) of BCM in the literature. The mean age at presentation was 57.81 years. Prior skin cancer, particularly melanoma (47%), accounted for 58% of pertinent medical history. Prominent clinical exam findings included raised (46%), ulcerated (73%) lesions larger than 1 cm (68%) in the lower extremities (35%). Median Breslow thickness of primary BCM cases was 2.5 mm. Hairpin vessels (75%) and structureless architecture (75%) were predominant on dermoscopy. Notable histopathology included large (47%), vacuolated (58%) cells with foamy cytoplasm (62%) and conspicuous nucleoli (27%). Positive S-100 immunohistochemistry (73%) was most frequently employed to diagnose BCM. We observed 47% primary and 53% metastatic BCM cases. Of metastatic BCMs, balloon ce