Histological evaluation of experimental AAA lesions revealed accumulated lipid in neointimal and medial layers, and analysis of human AAA lesions (n=5) obtained from open repair showed medial lipid deposition.
 
  In summary, we find that lipid deposition in the aortic wall is a feature of PPE-induced AAA in mice as well as human AAA lesions. Despite, our data do not support the hypothesis that hyperlipidemia contributes to AAA progression.
 In summary, we find that lipid deposition in the aortic wall is a feature of PPE-induced AAA in mice as well as human AAA lesions. Despite, our data do not support the hypothesis that hyperlipidemia contributes to AAA progression.Accurate detection of heavy metal stress on the growth status of plants is of great concern for agricultural production and management, food security, and ecological environment. A proximal hyperspectral imaging (HSI) system covered the visible/near-infrared (Vis/NIR) region of 400-1000 nm coupled with machine learning methods were employed to discriminate the tobacco plants stressed by different concentration of heavy metal Hg. After acquiring hyperspectral images of tobacco plants stressed by heavy metal Hg with concentration solutions of 0 mg·L-1 (non-stressed groups), 1, 3, and 5 mg·L-1 (3 stressed groups), regions of interest (ROIs) of canopy in tobacco plants were identified for spectra processing. Meanwhile, tobacco plant's appearance and microstructure of mesophyll tissue in tobacco leaves were analyzed. After that, clustering effects of the non-stressed and stressed groups were revealed by score plots and score images calculated by principal component analysis (PCA). Then, loadings of PCA and competiroups of tobacco plants, the other FS-LS-SVM, PCA-LS-SVM, and CARS-LS-SVM models were setup and offered relatively low accuracies of 55.56%, 51.11% and 66.67%, respectively. Performance of those 3 LS-SVM discriminative models was also poorly performing to differentiate 3 stressed groups of tobacco plants, which might be caused by low concentration of heavy metal and similar canopy (especially in fresh leaves) of plant. The achievements of the research indicated that HSI coupled with machine learning methods had a powerful potential to discriminate tobacco plant stressed by heavy metal Hg.Surface-enhanced Raman spectroscopy based on thioglycolic acid (TGA) functionalized silver-coated gold nanoparticles (Au@Ag-TGANPs) was developed for the facile screening of thiabendazole (TBZ) and ferbam (0.025-10 ppm) in liquid milk for the first time. Results showed that silver-coated gold nanoparticles (Au@AgNPs) with a core size of 32 nm and a shell thickness of 5 nm was successfully modified with 3 nm TGA. The sensitive Au@Ag-TGANPs could enhance TBZ and ferbam signals by factors of 6.4 × 104 and 9.8 × 104, respectively, and achieved the detection of TBZ and ferbam with limits of detection of 0.12 and 0.003 ppm, R2 of 0.988 and 0.9821, percent recoveries of 88-103% and of 87.2-103.5%, and relative standard deviations of 4.1-9.2% and 3.5-8.3%, respectively. The current simple and green method could thus be used to detect other unsafe chemicals in future studies.
  Fatigue is a physical and emotional state associated with certain aspects of nursing practice. The current study aimed to investigate the indirect effect of dispositional mindfulness on fatigue via emotional suppression in oncology female nurses.
 
  In a cross-sectional study, 137 female oncology nurses were recruited from several hospitals to complete baseline questionnaires. Emotional suppression, dispositional mindfulness and fatigue were assessed with the Weinberger Adjustment Inventory (WAI), Five Facet Mindfulness Questionnaire (FFMQ) and the Multidimensional Fatigue Inventory (MFI) respectively. A Mediation model was tested using structural equation modelling.
 
  Dispositional mindfulness was negatively associated with emotional suppression (β=-0.69, p=0.000).  https://www.selleckchem.com/products/vit-2763.html  In addition, emotional suppression was positively associated with fatigue (β=0.32, p=0.014). The mediation path was significant with emotional suppression fully mediating the relationship between dispositional mindfulness and fatigue (b=-0.20 [CI -0.01, -0.25].
 
  These results support the proposed model, and the assumption that emotional suppression may help facilitate the onset of fatigue or maintain it in female oncology nurses. The findings have implications for the use of brief mindfulness interventions aimed at the effective regulation of emotion in oncology nurses to aid in well-being and optimal nursing practice.
 These results support the proposed model, and the assumption that emotional suppression may help facilitate the onset of fatigue or maintain it in female oncology nurses. The findings have implications for the use of brief mindfulness interventions aimed at the effective regulation of emotion in oncology nurses to aid in well-being and optimal nursing practice.
  This study was undertaken to determine the effects of individualized education with support intervention on breast cancer patients' anxiety and depression while undergoing radiation therapy (RT). Moreover, the intervention was assessed for its feasibility in the context of Pakistan.
 
  A quasi-experimental design was used to conduct this study in RT department of a public hospital in Karachi. A total of 61 breast cancer patients receiving radiation as adjuvant therapy participated in the study. The experimental group (n=31) received individualized education with support in the form of face-to-face sessions and information booklet prior to the commencement of RT. In addition, the nurse remained available for the consultation during the RT sessions and on telephone throughout the RT period. However, the control group received only information booklet. Patients' anxiety and depression were measured in both of the groups before the commencement of RT, and at the completion of RT by using the Aga Khan University Anxiety and Depression Scale (AKUADS).
 
  A significant reduction was found in the overall mean anxiety and depression scores of the experimental group (p=0.000) from pre-test to post-test. The overall mean anxiety and depression scores of the control group showed no significant difference (p=0.187). The effect size of the intervention was large (Cohen's d=2.5).
 
  The intervention was effective in reducing anxiety and depression among breast cancer patients receiving RT. Replication of the study on a larger scale in multiple settings on other cancer patients is recommended.
 The intervention was effective in reducing anxiety and depression among breast cancer patients receiving RT. Replication of the study on a larger scale in multiple settings on other cancer patients is recommended.