https://www.selleckchem.com/products/i-191.html High-performance catalysts are extremely required for controlling NO emission via selective catalytic reduction (SCR), and to acquire a common structural feature of catalytic sites is one key prerequisite for developing such catalysts. We design a single-atom catalyst system and achieve a generic characteristic of highly active SCR catalytic sites. A single-atom Mo1/Fe2O3 catalyst is developed by anchoring single acidic Mo ions on (001) surfaces of reducible α-Fe2O3, and the individual Mo ion and one neighboring Fe ion are thus constructed as one dinuclear site. As the number of the dinuclear sites increases, SCR rates increase linearly but the apparent activation energy remains almost unchanged, evidencing the identity of the dinuclear active sites. We further design W1/Fe2O3 and Fe1/WO3 and find that tuning acid or/and redox properties of dinuclear sites can alter SCR rates. Therefore, this work provides a design strategy for developing improved SCR catalysts via optimizing acid-redox properties of dinuclear sites.Aging is characterized by a gradual loss of function occurring at the molecular, cellular, tissue and organismal levels. At the chromatin level, aging associates with progressive accumulation of epigenetic errors that eventually lead to aberrant gene regulation, stem cell exhaustion, senescence, and deregulated cell/tissue homeostasis. Nuclear reprogramming to pluripotency can revert both the age and the identity of any cell to that of an embryonic cell. Recent evidence shows that transient reprogramming can ameliorate age-associated hallmarks and extend lifespan in progeroid mice. However, it is unknown how this form of rejuvenation would apply to naturally aged human cells. Here we show that transient expression of nuclear reprogramming factors, mediated by expression of mRNAs, promotes a rapid and broad amelioration of cellular aging, including resetting of epigenetic clock, reduction of the inflammatory