https://www.selleckchem.com/products/GDC-0879.html The development of an Australian Indigenous-led bush products sector presents opportunities for Indigenous Australians to create new livelihoods, and build on existing enterprises, based on their unique knowledge systems and long established socio-cultural and environmental management practices. This review draws on Australian literature from 2005 to 2018 to establish a better understanding of the benefits that could result from the development of this sector in northern Australia; identify the key challenges that need to be addressed to facilitate sector development; and identify possible solutions. Insights reveal that while there are significant, and potentially self-sustaining opportunities offered by the development of the sector, these are unlikely to be realised without appropriate actions to resolve knowledge and skills gaps and address significant social, cultural and legal challenges. We propose a conceptual framework for the appropriate, sustainable and self-sustaining growth of the sector and end with policy and research recommendations to support growth.Chronic diarrhea is a frequent presenting symptom, both in primary care medicine and in specialized gastroenterology units. It is estimated that more than 5% of the global population suffers from chronic diarrhea. and that about 40% of these subjects are older than 60 years. The clinician is frequently faced with the need to decide which is the best therapeutic approach for these patients. While the origin of chronic diarrhea is diverse, impairment of intestinal barrier function, dysbiosis. and mucosal micro-inflammation are being increasingly recognized as underlying phenomena characterizing a variety of chronic diarrheal diseases. In addition to current pharmacological therapies, there is growing interest in alternative products such as mucoprotectants, which form a mucoadhesive film over the epithelium to reduce and protect against the development of