https://www.selleckchem.com/products/blu-554.html e. visual color, color saturation and photosynthetic pigment concentrations) were only seen concurrently with tissue loss (i.e. at ≥2.5 mg/L nominal concentration BP-3). Polyp retraction, the most sensitive endpoint of this test, was seen to be a sub-lethal behavioral response to BP-3 exposure. Using the calculated LC50 with measured concentrations from a high-quality UV filter monitoring study in Hawaii, a preliminary, conservative risk quotient for BP-3 was calculated at 0.032. These results suggest that BP-3 likely does not pose an acute risk of mortality to G. fascicularis and additional testing is required to determine sublethal impacts of BP-3 under environmentally relevant concentrations and longer-term chronic exposures. This study highlights complications in conducting toxicity tests with organic UV filters including under-estimations of exposure concentrations and provides recommendations to improve these methods for better comparisons between studies.We all know that, nowadays, physics and philosophy are housed in separate departments on university campuses. They are distinct disciplines with their own journals and conferences, and in general they are practiced by different people, using different tools and methods. We also know that this was not always the case up until the early 17th century (at least), physics was a part of philosophy. So what happened? And what philosophical lessons should we take away? We argue that the split took place long after Newton's Principia (rather than before, as many standard accounts would have it), and offer a new account of the philosophical reasons that drove the separation. We argue that one particular problem, dating back to Descartes and persisting long into the 18th century, played a pivotal role. The failure to solve it, despite repeated efforts, precipitates a profound change in the relationship between physics and philosophy. The culprit is the problem of collisi