To compare patient adaptation to and satisfaction with new complete dentures fabricated with a duplication construction protocol (DCP) using two different occlusal schemes, bilateral balanced (BBO) and lingualized (LO).
 
  Twenty complete denture wearers who received replacement DCP dentures participated in this study. Ten participants received complete dentures with a BBO scheme, and the other 10 received DCP dentures with an LO scheme. All of them evaluated their prostheses subjectively through the Oral Health Impact Profile-20 (OHIP-20) and the Complete Denture Satisfaction (CDS) questionnaires before treatment and at 3- and 6-month posttreatment intervals. The new prostheses were also normatively evaluated by recording the location and number of sore spots present at the scheduled early adjustment visits. Data were analyzed with nonparametric tests to identify differences in patient responses between groups and within each group at each evaluation interval point (α = .05).
 
  The within-group comparisons revealed statistically significant improvement for both denture groups (P < .05), while the between-group comparisons did not record statistically significant differences at the overall evaluation period (P > .05). Significant within-group differences were recorded in the pain, functional limitation, and psychologic disability domains of the OHIP-20 questionnaire and the comfort, esthetics, and stability domains of the CDS questionnaire.
 
  The patients' adaptation to and satisfaction with newly constructed DCP dentures improved significantly for both BBO and LO denture groups throughout the evaluation period. The mean number of early adjustment visits was equal for both the BBO and LO denture groups.
 The patients' adaptation to and satisfaction with newly constructed DCP dentures improved significantly for both BBO and LO denture groups throughout the evaluation period. The mean number of early adjustment visits was equal for both the BBO and LO denture groups.
  To report on pilot tests for a planned study on single implant-supported crowns made from different restorative materials using finite element analysis (FEA) and in vitro load-to-failure testing.
 
  Within this pilot study, FEA was conducted using Ansys 2019 R2 to simulate stress and deformation for implant-supported crowns made of lithium disilicate ceramic (LiS2) and zirconia (3Y-TZP). Additionally, an in vitro load to failure test was conducted using two specimens per group to evaluate the failure mode and to confirm the findings from the FEA.
 
  FEA revealed stress areas at the palatal cervical areas of the crowns. In the load to failure test, both hybrid abutment crowns made of LiS2 fractured (410 N and 510 N) before plastic deformation of the metal implant components occurred. The monolithic hybrid abutment crowns made of 3Y-TZP did not fracture until tests were interrupted at 646-N and 690-N occlusal force, when plastic deformation of the metal implant components was visually observed.
 FEA revealed stress areas at the palatal cervical areas of the crowns. In the load to failure test, both hybrid abutment crowns made of LiS2 fractured (410 N and 510 N) before plastic deformation of the metal implant components occurred. The monolithic hybrid abutment crowns made of 3Y-TZP did not fracture until tests were interrupted at 646-N and 690-N occlusal force, when plastic deformation of the metal implant components was visually observed.
  To evaluate the efficacy of manual and machine-aided cleaning to remove matured plaque from removable partial dentures (RPD).
 
  A total of 32 patients with bilateral free-end saddle RPDs were included. The plaque was stained, and the RPD was photographed on all sides. One saddle was randomly allocated to manual cleaning, while the other was allocated to no cleaning. The patient manually cleaned the saddle by applying a denture brush and gel. The whole RPD was then cleaned with the aide of a machine using a rotating needle device. After each step, plaque dyeing and photographing were repeated. The plaque proportions (% pixel) were measured using special software. For statistical analysis, mixed models were used to adjust for baseline covariates, including plaque and surfaces, and to cover all time points.
 
  The mean plaque area without cleaning at the fitting surface was higher than at the buccal/lingual surfaces (32.8% [95% CI 28.1% to 36.4%] vs 15.3% [13.1% to 17.4%], respectively). Manual cleaning was not substantially better than no cleaning (4.6% [-0.1% to 9.2%] for the difference at fitting surfaces; disclaiming a substantial difference of > 10%; the difference found was even smaller at buccal/lingual surfaces). Machine-aided cleaning was substantially better than manual cleaning (16.1% [12.0% to 20.2%] for the difference at fitting surfaces and 7.3% [4.6% to 10.0%] at buccal/lingual surfaces). The combination of manual and machine-aided cleaning was not better than machine-aided cleaning alone (-0.2% [-2.6% to 2.1%] difference at fitting surface).
 
  Manual cleaning is insufficient in removing matured denture plaque. Machine-aided cleaning is clearly superior to manual cleaning, especially at fitting surfaces.
 Manual cleaning is insufficient in removing matured denture plaque. Machine-aided cleaning is clearly superior to manual cleaning, especially at fitting surfaces.
  To assess the retention and adaptation of milled and printed denture bases and to compare them to conventional ones.
 
  A total of 24 completely edentulous patients were selected. For each patient, three maxillary denture bases were constructed. Three groups were defined according to fabrication technique group I = denture bases were constructed by a conventional technique; group II = denture bases were milled from prepolymerized blocks of polymethyl methacrylate; and group III = denture bases were fabricated by a 3D printing technique. A digital force gauge was used for measuring the retention of the denture bases intraorally, while Geomagic Control X 64 software was used to evaluate the adaptation of the denture bases with their corresponding master casts. Analysis of variance for repeated measures was used for comparison among the groups, followed by pairwise comparison with Bonferroni correction as a post hoc test.  https://www.selleckchem.com/products/dinaciclib-sch727965.html  The significance level was set at α = .05.
 
  Statistical analysis showed significant differences among the three groups regarding retention and adaptation.