https://www.selleckchem.com/products/gs-441524.html Pregnancy is associated with physiological alterations in insulin sensitivity and lipid metabolism. This study investigates the associations between pregestational body mass index (pBMI) and the rate of gestational weight gain (rGWG) in the second trimester with the biomarkers of lipid, fatty acids metabolism and insulin resistance. Sixty nine pregnant women followed. The body weights of the pregnant women were measured and blood samples were obtained at 11-14th and 24-28th weeks of pregnancy. Glucose, total cholesterol, triglyceride, HDL cholesterol, LDL cholesterol, insulin levels and fatty acids were measured. Rate of GWG (kg/week) and The Homeostasis Model Assessment for Insulin Resistance (HOMA-IR) were calculated. The pregnant women were stratified according to their pBMI and the 2nd trimester rGWG. The rate of GWG was significantly higher for the group with pBMI<25, compared to the group with pBMI≥25 (p=0.024). Triglyceride, total cholesterol, LDL and HDL cholesterol were significantly increasnges in lipid metabolism and the development of insulin resistance. Pregestational BMI was shown to have a stronger influence on lipid profile, insulin resistance, and fatty acids than rGWG.Mesoporous metal sulfides (MMSs) with high surface areas and large pore volumes show great potential in many applications such as gas sensing, photodetection, and catalysis. However, the synthesis of MMSs is still challenging due to the uncontrollable fast precipitation between metal ions and S2- ions and the large volume contraction during the conversion of metal precursors to sulfides. Here, a general polymer-oriented acid-mediated self-assembly method to synthesize highly crystalline MMSs (e.g., ZnS, CdS, Ni3 S4 , CuS, and Znx Cd1- x S) by using polyethylenimine (PEI) as pore-forming agent is reported. In this method, acetic acid is designed as pH regulator and coordination agent to control the interactions between inorganic precu