https://www.selleckchem.com/products/gdc-0068.html Analyses of ES data indicated that the IATP conditions yielded greater increases in use of adaptive coping skills during temptation episodes than did the MET-CBT conditions. Mediation analyses supported the hypothesis that momentary use of coping skills mediates the effects of IATP on use or non-use of marijuana in the hours following a temptation episode. Use of an individualized coping treatment approach results in lower use of marijuana in high-risk situations, and actual utilization of adaptive coping appears to be a mechanism of that effect. (PsycInfo Database Record (c) 2021 APA, all rights reserved). Use of an individualized coping treatment approach results in lower use of marijuana in high-risk situations, and actual utilization of adaptive coping appears to be a mechanism of that effect. (PsycInfo Database Record (c) 2021 APA, all rights reserved). Social context plays a critical role in youth cannabis use. Yet few studies have examined if and when social contexts shift during cannabis use treatment. This study examined daily shifts in youths' social contexts with the goal of characterizing how specific social contexts (e.g., time with cannabis-using friends or siblings) relate to cannabis craving and use during cannabis treatment. Participants were 65 cannabis users (51% male), ages 15-24 years, who participated in a double-blind randomized clinical trial that tested the effects of motivational enhancement and cognitive behavioral therapies plus either adjunctive pharmacotherapy or placebo on cannabis craving and use. Ecological momentary assessment (EMA) data, collected from a pre-randomization period through the completion of the six-week intervention, assessed youths' social contexts, cannabis use, and craving. Time-varying effects models identified shifts in social contexts during treatment. Overall, time spent with cannabis-using friends andreported greater craving and use. This research supports inc