https://www.selleckchem.com/products/gusacitinib.html This study was conducted during a period of lockdown and ban on social gatherings, including religious gatherings, in Ghana. The restrictions were instituted in response to the COVID-19 pandemic. The purpose of the study was to understand how the well-being of Christian church leaders was impacted during the prohibition in terms of aspects of their vocation and religious practices. Fourteen Christian church leaders located in urban and rural settings in Ghana, with 5 to 32 years of experience, discussed how they and their families were impacted by the ban on religious gatherings in Ghana. Findings revealed negative impacts of the COVID-19 restrictions, including spiritual slacking, loss of fellowship, disruption of normal routine, pandemic anxiety, and financial stress. Positive impacts included increased faith, relief/reduced stress, and increased family time. These findings are discussed from psychological trauma and disaster response perspectives.The scientific ecosystem relies on citation-based metrics that provide only imperfect, inconsistent and easily manipulated measures of research quality. Here we describe DELPHI (Dynamic Early-warning by Learning to Predict High Impact), a framework that provides an early-warning signal for 'impactful' research by autonomously learning high-dimensional relationships among features calculated across time from the scientific literature. We prototype this framework and deduce its performance and scaling properties on time-structured publication graphs from 1980 to 2019 drawn from 42 biotechnology-related journals, including over 7.8 million individual nodes, 201 million relationships and 3.8 billion calculated metrics. We demonstrate the framework's performance by correctly identifying 19/20 seminal biotechnologies from 1980 to 2014 via a blinded retrospective study and provide 50 research papers from 2018 that DELPHI predicts will be in the top 5% of time-rescaled node c