BACKGROUND Humans interact with multiple stimuli across several modalities each day. The "redundant signal effect" refers to the observation that individuals respond more quickly to stimuli when information is presented as multisensory, redundant stimuli (e.g., aurally and visually), rather than as a single stimulus presented to either modality alone. Studies of alcohol effects on human performance show that alcohol induced impairment is reduced when subjects respond to redundant multisensory stimuli. However, redundant signals do not need to involve multisensory stimuli to facilitate behavior as studies have shown facilitating effects by redundant unisensory signals that are delivered to the "same sensory" (e.g., two visual or two auditory signals). METHODS The current study examined the degree to which redundant visual signals would reduce alcohol impairment and compared the magnitude of this effect with that produced by redundant multisensory signals. On repeated test sessions, participants (n = 20) received placebo or 0.65 g/kg alcohol and performed a two-choice reaction time task that measured how quickly participants responded to four different signal conditions. The four conditions differed by the modality of the target presentation visual, auditory, multisensory, and unisensory. RESULTS Alcohol slowed performance in all conditions and reaction times were generally faster in the redundant signal conditions. Both multisensory and unisensory redundant signals reduced the impairing effects of alcohol compared with single signals. CONCLUSIONS These findings indicate that the ability of redundant signals to counteract alcohol impairment does not require multisensory input. Duplicate signals to the same modality can also reduce alcohol impairment. Gastrointestinal (GI) problems affect half of Western populations. Symptoms can vary from frequent reflux to irritable bowel syndrome. The Nutrition Care (NC) Gut Relief Formula contains a combination of herbs and nutrients including curcumin, Aloe vera, slippery elm, guar gum, pectin, peppermint oil, and glutamine shown to benefit the GI system. The 16-week pre-post study tested the hypothesis that the NC Gut Relief Formula would be tolerable and effective in improving GI symptoms and gut health in adults with digestive disorders. A total of 43 participants completed the study. After a control phase, participants took 5 g/d and then 10 g/d of the formula for 4 weeks. GI symptoms and GI health were assessed by a series of validated questionnaires, for example, Leeds Dyspepsia Questionnaire, Bristol Stool Chart, Birmingham IBS Symptom Questionnaire, and by intestinal permeability and gut microbiota profile. The NC Gut Relief Formula significantly improved the frequency and severity of upper and lower GI symptoGut Relief Formula significantly improved GI symptoms and associated quality of life over 3 months while reducing intestinal permeability, improving the microbial profile, reducing the need for reflux medication, and enabling the consumption of previous food triggers. Nutritional status can affect the linear growth of bones during puberty by affecting growth plate (GP) chondrocytes. We hypothesized that there is a relationship between dietary patterns and bone age on girls who have experienced height loss. This cross-sectional study was conducted on 350 girls aged 12-13 years with open GP, and major dietary patterns were determined using the factor analysis method. Dual-energy x-ray absorptiometry measurement of participant's wrist was performed to determine GP openness and bone age. In the present study, 70.3% of participants had bone age below chronological age. Three major dietary patterns-healthy, high sugar and salt, and Western diet-were identified using findings of dietary intake. Adherence to the healthy diet led to significant increase in height, weight, body mass index, and other components of body composition such as lean body mass (P less then .001).  https://www.selleckchem.com/MEK.html  Among these dietary patterns, we found only a significant association between healthy diet and difference between bone and chronological age (B = -0.106). In the present study, adherence to a healthy diet was associated with increase in bone age (P = .02). Healthy dietary pattern with an emphasis on enough intake of plant protein and white meat was associated with better linear growth. Color Doppler (CD) ultrasound has been commonly employed in biomedical field to get hemodynamic information. However, reliable diagnostic evaluation and criteria for vascular diseases may not be provided due to technical limitations of CD, including single-directional measurement, aliasing, and limited imaging conditions. In this study, adaptive hybrid (AH) scheme is proposed to enhance measurement accuracy of conventional CD. It can improve the accuracy of velocity field measurement by replacing erroneous vectors in the measured CD results with the correct vectors obtained from a speckle image velocimetry (SIV) technique. The performance of the proposed AH technique was validated through in vitro experiments for various flow rates and insonation angle conditions, comparing conventional velocimetry techniques. The in vitro experiments demonstrated that the AH technique could measure flow velocity with better accuracy than the CD with bias errors of below 0.7 mm/s. The clinical applicability of the AH was also validated by measuring venous flows at human lower extremity, checking constant volumetric flow rates. Flow rates measured by the AH were maintained along the vein, while the CD and SIV results varied. As a result, the AH can provide improved measurement accuracy without installing a new supplementary equipment. It would be effectively utilized for analyzing flow dynamics and diagnosing valve-related disease. OBJECTIVES Behaviour change programmes (BCPs) for pregnant women are frequently implemented as part of health promotion initiatives. At present, little is known about the types of behaviour change programmes that are being implemented and whether these programmes are designed and delivered in accordance with the principles of high quality maternity care. In this scoping review, we provide an overview of existing interventions related to behaviour change in pregnancy with a particular emphasis on programmes that include empowerment components to promote autonomy and woman-led decision-making. METHODS A systematic search strategy was applied to check for relevant papers in August 2017 and again in October 2018. RESULTS Thirty studies met the criteria for inclusion. These studies addressed weight management, smoking cessation, general health education, nutrition, physical activity, alcohol consumption and dental health. The main approach was knowledge gain through education. More than half of the studies (n = 17) included three or more aspects of empowerment as part of the intervention.