Our author's Cognitive Neuroscience of Creativity Lab at Penn State uses brain imaging and behavioral experiments to examine how creative thinking works in different contexts and domains, from the arts to the sciences to everyday life. His article examines the part of the brain that directs creative thought and asks the million-dollar question Can creativity be enhanced? Copyright 2020 The Dana Foundation All Rights Reserved.Our author- the director of the Social Neuroscience and Health Laboratory at the University of North Carolina-examines new research that ties income and other factors to stress and other emotional responses. Does how we perceive our social standing impact our life expectancy and heart health? Are there interventions available to develop emotion regulation strategies? Copyright 2020 The Dana Foundation All Rights Reserved.Solving the mystery of Alzheimer's disease is one of the most important-and elusive-challenges in medicine. New cutting-edge research by our author's lab at Sanford Burnham Prebys Medical Discovery Institute in La Jolla, California points to unique genomic changes within single cells of the brain, called somatic gene recombination, as a potential new factor in finding answers. Copyright 2019 The Dana Foundation All Rights Reserved.The total cost of Parkinson disease (PD), which affects nearly 1 million people in the US is $52 billion every year, with $25.4 billion attributable to direct medical costs such as hospitalizations and medication, and $26.5 billion in non-medical costs like missed work, lost wages, early forced retirement, and family caregiver time. The more we know about PD's non-motor symptoms-depression, dementia, fatigue, and others-the better we can treat, and perhaps find a cure, for this neurological disorder. Copyright 2019 The Dana Foundation All Rights Reserved.Neuroaesthetics is a new and rapidly expanding field of research that is aimed at the intersection of psychological aesthetics, biological mechanisms, and human evolution. Our author, a pioneer in this young and exciting field, tells us how music, art, theater, dance, literature, landscape, and media have the power to help treat any number of disorders and improve one's quality of life. Copyright 2019 The Dana Foundation All Rights Reserved.Devices in and out of the brain that can stimulate the nervous system through electric current are now being used to treat depression, movement disorders, and chronic pain. Our author, a Stanford School of Medicine clinical associate professor who is senior scientific research director for Defense and Veterans Brain Injury Center at the VA Palo Alto Health Care System, provides insight on the many neuromodulation strategies now available to treat brain injury and the potential of further research to accomplish much more. Copyright 2019 The Dana Foundation All Rights Reserved.The silent, often subconscious conversation that is taking place inside us is one of the most vital communications we will ever find ourselves engaged in. It's the dialogue of emotion-based signals between our hearts and our brains, also known as the heart-brain connection. Our author tells us what research has uncovered and some of the keys to a longer, healthier life. Copyright 2019 The Dana Foundation All Rights Reserved.Spinal muscular atrophy is the number one genetic cause of infant death. Until recently, half the babies born with it would die before their second birthdays, their hearts and lungs becoming too weak to continue. Medical care improved the odds somewhat, but new discoveries and therapeutic developments have improved survival rates significantly-and more good news may be on the horizon. Copyright 2019 The Dana Foundation All Rights Reserved.When we consider the health and welfare of our children, few issues are of more concern than the risk and consequences of head trauma in sports. From participation in male-dominated football and hockey to girls soccer and softball, repeated impacts to the head that do not produce recognized concussion is the cutting edge of sports head injury research.  https://www.selleckchem.com/products/Metformin-hydrochloride(Glucophage).html  Our author, a leading researcher in this field, provides the latest on what we know and don't know on this relatively new frontier of neuroscience. Copyright 2019 The Dana Foundation All Rights Reserved.Brain-machine interface-once the stuff of science fiction novels-is coming to a computer near you. The only question is How soon? While the technology is in its infancy, it is already helping people with spinal cord injuries. Our authors examine its potential to be the ultimate game changer for any number of neurodegenerative diseases, as well as behavior, learning, and memory. They take the temperature of where the technology is, where it is going, and the inevitable ethical and regulatory implications. Copyright 2019 The Dana Foundation All Rights Reserved.What happens to your brain when you multitask? Does your brain slow down? Do you feel increased levels of stress? Why are some people better at it than others? Our authors supply the answers to some of these questions and provide the latest on what happens to the brain when you try to handle more than one task at a time. Copyright 2019 The Dana Foundation All Rights Reserved.Along with the rising number of people suffering from dementia and Alzheimer's disease (due to longer life spans) come two main concerns finding remedies and helping them live comfortable and contented lives. Our authors examine the latest research on what is called "retro environments" and "reminiscence therapy," which includes health-care communities that offer elements of nostalgia, as well as music, objects, and photographs from one's past. Copyright 2019 The Dana Foundation All Rights Reserved.Background Red oak pollen is an important cause of allergic respiratory disease and it is widely distributed in North America and central Europe. To date, however, red oak pollen allergens have not been identified. Here, we describe the allergenic protein profile from red oak pollen. Methods Total proteins were extracted from red oak pollen using a modified phenolic extraction method, and, subsequently, proteins were separated by two-dimensional gel electrophoresis (2DE) for both total protein stain (Coomassie Blue) and immunoblotting. A pool of 8 sera from red oak sensitive patients was used to analyze blotted proteins. Protein spots were analyzed by Mass Spectrometry. Results Electrophoretic pattern of total soluble proteins showed higher intensity bands in the regions of 26-40 and 47-52 kDa. Two dimensional immunoblots using pool sera from patients revealed four allergenic proteins spots with molecular masses in the range from 50 to 55 kDa. Mass spectrometry analysis identified 8 proteins including Enolase 1 and Enolase 1 chloroplastic, Xylose isomerase (X1 isoform), mitochondrial Aldehyde dehydrogenase, UTP-Glusose-1-phosphate uridylyltransferase, Betaxylosidase/alpha-l-arabinofuranosidase and alpha- and beta subunits of ATP synthase.