https://www.selleckchem.com/products/Benserazide-hydrochloride(Serazide).html From the perspective of affected families a proactive early individual and reliable care coordination by a constant contact person is essential for a good discharge management. From the perspective of affected families a proactive early individual and reliable care coordination by a constant contact person is essential for a good discharge management. To prospectively compare the short-term periodontal effects and survival rates of mandibular lingual canine-to-canine Memotain (CA-Digital, Mettmann, Germany) and five-stranded bonded retainers. In all, 52patients requiring retention after orthodontic treatment were assigned to 2study groups (n = 26 in each group). Retention was provided by Memotain retainers which were fabricated digitally using CAD-CAM (computer-aided design and computer-aided manufacturing) technology in the first group and by five-stranded retainers which were fabricated manually using a conventional bending method in the second group. The patients were examined at the following time points 1week, 1month, 3months and 6months. Plaque index, gingival index, probing depth, marginal recession, bleeding on probing, failure rate per tooth, and survival rate of retainer wires were analyzed by Mann-WhitneyU, Friedman, Wilcoxon signed-rank, and χ tests. The differences between the groups were nonsignificant for plaque index, gingival index, probing depth, marginal recession, bleeding on probing, failure rate per tooth and survival rate of retainer wires. Significant differences were observed within the groups throughout the follow-up period for plaque index and probing depth. The survival rates of retainer wires were 77% for the Memotain retainers and 73% for the five-stranded retainers for the 6‑month follow-up period. Periodontal outcomes and survival rates of Memotain and five-stranded mandibular lingual bonded retainers were similar. Furthermore, periodontal health was maintai