https://www.selleckchem.com/products/gw5074.html The mechanical strength of VCM and GCM specimens is higher than that of MCM specimens under the same compaction work and the optimum asphalt aggregate ratio. With the increase in compaction work, the mechanical properties of SMA-13 mixture are improved at the same compaction method and the optimum asphalt aggregate ratio. The aggregate gradation of the SMA-13 mixture before and after compacted using VCM and GCM changes minimally compared with that of the SMA-13 mixture compacted by MCM. Thus, the compaction methods of VCM65 and GCM130 were recommended for SMA-13 mixture design. Peru is the country with the world's highest COVID-19 death rate per capita. Characteristics associated with increased mortality among adult patients with COVID-19 pneumonia in this setting are not well described. Retrospective, single-center cohort study including 1537 adult patients hospitalized with a diagnosis of SARS-CoV-2 pneumonia between May 2020 and August 2020 at a national hospital in Lima, Peru. The primary outcome measure was in-hospital mortality. In-hospital mortality was 49.71%. The mean age was 60 ± 14.25 years, and 68.38% were males. We found an association between mortality and inflammatory markers, mainly leukocytes, D-dimer, lactate dehydrogenase, C-reactive protein and ferritin. A multivariate model adjusted for age, hypertension, diabetes mellitus, and corticosteroid use demonstrated that in-hospital mortality was associated with greater age (RR 2.01, 95%CI 1.59-2.52) and a higher level of oxygen requirement (RR 2.77, 95%CI 2.13-3.62). Conclusions In-hospital mortality among COVID-19 patients in Peru is high and is associated with greater age and higher oxygen requirements. In-hospital mortality was 49.71%. The mean age was 60 ± 14.25 years, and 68.38% were males. We found an association between mortality and inflammatory markers, mainly leukocytes, D-dimer, lactate dehydrogenase, C-reactive protein and ferritin. A multiv