https://www.selleckchem.com/products/mycro-3.html This study evaluated the earthquake warning system for high-speed trains using onboard accelerometers instead of expensive seismometers. Onboard accelerometers measure the train data additional to the earthquake acceleration. The measured earthquake acceleration could also be modified by railroad-supporting bridges. To develop the data analysis system, the virtual onboard data sets are synthesized using the train acceleration data and earthquake data. Not only the earthquake acceleration data but also the earthquake responses of bridges are used for the virtual onboard data synthesis. For the analysis of synthesized data, the short-time Fourier Transform (STFT), the wavelet transform (WT), and Wigner-Ville Distribution (WVD) methods have been compared. Results show that WVD provides the best detection performance while the computational costs are large.A comprehensive understanding of the behaviour of Glycosaminoglycans (GAGs) combined with imaging or therapeutic agents can be a key factor for the rational design of drug delivery and diagnostic systems. In this work, physical and thermodynamic phenomena arising from the complex interplay between GAGs and contrast agents for Magnetic Resonance Imaging (MRI) have been explored. Being an excellent candidate for drug delivery and diagnostic systems, Hyaluronic acid (HA) (0.1 to 0.7%w/v) has been chosen as a GAG model, and Gd-DTPA (0.01 to 0.2 mM) as a relevant MRI contrast agent. HA samples crosslinked with divinyl sulfone (DVS) have also been investigated. Water Diffusion and Isothermal Titration Calorimetry studies demonstrated that the interaction between HA and Gd-DTPA can form hydrogen bonds and coordinate water molecules, which plays a leading role in determining both the polymer conformation and the relaxometric properties of the contrast agent. This interaction can be modulated by changing the GAG/contrast agent molar ratio and by acting on the organization of th