Brucellosis is the most widespread zoonosis in the world. In Spain its incidence has decreased considerably in recent years thanks to the social and health measures carried out. 40 cases of brucellosis have been reported in humans in 2018, representing a rate of 0.09 per 100,000 inhabitants. The objective of the study was to highlight the importance of epidemiological suspicion, as well as the screening of relatives for the diagnosis of the disease.
 
  A descriptive study of a family outbreak of imported brucellosis was carried out. Five members of the same family were evaluated after the diagnosis of brucellosis in a patient in the Health Area III of Zaragoza, in May 2019. The relatives of the patient and the health center were contacted by telephone to investigate the possibility of involvement of the relatives with whom he had traveled and lived in Morocco.
 
  In a scenario with a low frequency of disease such as our country at the present time, family screening, after an initial diagnosis of imported brucellosis, allowed the detection and treatment of four members of the same family of Maghreb origin. They were infected during a trip to their place of origin in April 2019, a month in which they lived in rural areas in contact with animals (sheep, goats, cows) and consumed dairy and meat products. The appearance of presented symptoms was temporally consistent with the incubation period of the disease.
 
  Emphasize the importance of active surveillance and screening in relatives of patients diagnosed with Brucellosis, since they generally share exposures to a common source.
 Emphasize the importance of active surveillance and screening in relatives of patients diagnosed with Brucellosis, since they generally share exposures to a common source.
  One of the adverse drug reactions (ADR) can be the Ototoxicity, either in a cochlear level or in a vestibular one. This may cause an incapacitating symptomatology due to a hearing impairment or deafness, tinnitus, or a vertiginous syndrome. The objective of this work was to analyze the notifications of ototoxic ADRs registered in the FEDRA database of the Spanish Pharmacovigilance System for Medicinal products for Human Use (SEFV-H), manifested as tinnitus, describing epidemiological and prognostic factors, as well as active principles and associated therapeutic groups.
 
  An observational retrospective study based on the incoming registers in the FEDRA database of the SEFV-H, with tinnitus symptomatology due to ototoxicity between 1984 and 2017 has been carried out. SPSS v.20.0 program has been used for the descriptive and inferential statistics searching elements related to the emergence, seriousness or recuperation of the tinnitus.
 
  A total of 662 patients notifications were obtained with 899 suspected dl ototoxicity may determine an important limitation on the patient.  https://www.selleckchem.com/products/ly3023414.html  A vestibular and cochlear function monitoring must be carried out on patients under treatment with high ototoxicity drugs. The task of the pharmacovigilance seems to be essential, by spreading its results and stimulating the ADR notifications in order to identify pharmacological threats.
  Interventions for the health promotion and prevention of HIV infection and other sexually transmitted infections (STIs) are not being effective. I have analyzed the risk behaviors, the effectiveness of the campaigns, and the effectiveness of the channels, to determine the strategic keys of an effective communication. The aim of this work was to identify critical points and opportunities for communication improvement to promote behavioral changes and adoption of healthy lifestyles aimed at preventing HIV infections and other STIs.
 
  Target audiences, channels, terminology used in the media, campaigns and behavior surveys were analyzed. The analysis was completed using the Focus Group's qualitative research technique aimed at target audiences, made up of young people between 16-18 years old, and men who have sex with other men (MSM).
 
  Young people do not have quality information and do not distinguish reliable sources to make decisions. The terminology used in the media does not respond to the current epidemiological situation. The campaigns go unnoticed, the messages are very general, the channels are not appropriate, and they do not achieve behavioral changes. Focus groups are very useful for analyzing critical points and insights, which cannot be measured with quantitative methods.
 
  A new communication model is necessary for prevention of HIV and STIs, with the participation of the target audience to make the problem visible, transmit quality information, train communicators, adapt messages and channels, and evaluate interventions through Focus Groups of key populations.
 A new communication model is necessary for prevention of HIV and STIs, with the participation of the target audience to make the problem visible, transmit quality information, train communicators, adapt messages and channels, and evaluate interventions through Focus Groups of key populations.
  In spite of technical advances, hip fracture causes high mortality in the elderly. We wanted to know early surgery influence to mortality during admission, one year and after five years, as well as readmissions at one month and one year. We also wanted to know how dependence and Health-Related Quality of Life (HRQOL) evolved in the twelve months of follow-up and what factors were associated with poor patient evolution.
 
  A prospective observational study was made in patients over 65 years of age treated for osteoporotic hip fracture in a level III hospital between 2010- 2012, with consecutive sampling. We evaluated functionality (Barthel) and quality of life (EuroQol-5D) basal (before fracture), within 30 days, within six and twelve months; readmissions within the 30 days and within one year; and mortality during admission; within one and five years. We used the statistical program SPSS Version 25.0 for the statistical analysis.
 
  We followed 327 patients of 82.9 (SD 6.9) years of means, 258 (78.9%) were woer in the six months, remaining at twelve, without reaching the baseline value. The results in mortality and readmissions per year are worse for men and older. Early surgery does not reduce mortality, but re-admissions to the year.