https://www.selleckchem.com/products/fluorofurimazine.html We aimed to study whether islet autoantibody type marks differential characteristics at the time of type 1 diabetes (T1D) diagnosis. We studied 711 children with newly diagnosed autoimmune T1D. We compared demographic (sex, age, race/ethnicity), clinical (pubertal development, BMI percentile, diabetic ketoacidosis [DKA]) and laboratory (glucose, hemoglobin A1c [HbA1c], C-peptide, tissue transglutaminase antibodies [tTGA], thyroglobulin antibodies, and thyroid peroxidase antibodies [TPOA]) characteristics by presence/absence of autoantibodies to insulin (IAA), GAD65 (GADA), or IA-2/ICA512 (IA-2A). Islet autoantibody titers were evaluated among the children positive for the relevant autoantibody type. We used multivariable analysis to adjust for potential confounders. IAA+ was statistically associated with younger age (p< 0.0001) and lower HbA1c (p= 0.049) while Tanner stage, GADA status and number of positive islet autoantibodies were not significant in the multivariable model. GADA+ was associated wintibody type.A photocharge/discharge strategy is proposed to initiate the WO3 photoelectrode and suppress the main charge recombination, which remarkably improves the photoelectrochemical (PEC) performance. The photocharged WO3 surrounded by a 8-10 nm overlayer and oxygen vacancies could be operated more than 25 cycles with 50 h durability without significant decay on PEC activity. A photocharged WO3 /CuO photoanode exhibits an outstanding photocurrent of 3.2 mA cm-2 at 1.23 VRHE with a low onset potential of 0.6 VRHE , which is one of the best performances of p-n heterojunction structure. Using nonadiabatic molecular dynamics combined with time-domain DFT, we clarify the prolonged charge carrier lifetime of photocharged WO3 , as well as how electronic systems of photocharged WO3 /CuO semiconductors enable the effective photoinduced electrons transfer from WO3 into CuO. This work provides a feasible route to addr