https://osimertinibinhibitor.com/connection-between-gstt1-genotype-for-the-cleansing-of-just-one3-butadiene-produced-diepoxide-and/ Despite its promising potential in cancer therapy, synergistic photothermal/chemodynamic therapy continues to be underdeveloped pertaining to the usage of metal-organic products under 2nd near-infrared (NIR-II) laser excitation. Herein, we report a three-dimensional system built via the metal coordination between catechol-functionalized aza-boron dipyrromethenes and metal ions (ABFe), that was additional encapsulated by F127 to have ABFe nanoparticles (NPs) for combined photothermal/chemodynamic therapy. ABFe NPs exhibited intense consumption into the NIR-II range and negligible fluorescence. Upon 1064 nm laser irradiation, ABFe NPs showed high photothermal conversion efficiency (PCE = 55.0%) and exemplary photothermal stability. The results of electron spin resonance spectra and o-phenylenediamine chromaticity spectrophotometry proved that ABFe NPs were capable of creating harmful reactive oxygen species from hydrogen peroxide for chemodynamic therapy, that was promoted by photothermal overall performance. Notably, in vitro as well as in vivo experiments demonstrated the fantastic potential of ABFe NPs in photoacoustic imaging and photothermal-enhanced chemodynamic therapy under NIR-II laser irradiation. Consequently, the present work presents a prospective NIR-II excitation therapeutic nanomedicine for combination treatment, providing a novel technique for simultaneously achieving extended NIR consumption of aza-BODIPY and improved chemodynamic treatment with metal-organic materials.The aryl ketones, 9-fluorenone (fluor), 9-xanthenone (xanth) and 9,10-anthraquinone (anth), were reacted with β-diketiminato dimagnesium(I) compounds, [2 ] (Ar Nacnac=[HC(MeCNAr)2 ]- , Ar=mesityl (Mes) or 2,6-diisopropylphenyl (Dip)). This provided steady magnesium ketyl complexes that are monomeric, [(Ar Nacnac)(DMAP)Mg(fluor⋅)] (Ar=Mes or Dip, DMAP=4-dim