https://www.selleckchem.com/products/MLN8237.html COVID-19 pandemic outbreak is an unprecedented shock throughout the world, which has generated a massive social, human, and economic crisis. Identification of risk factors is crucial to prevent the COVID-19 spread by taking appropriate countermeasures effectively. Therefore, this study aimed to identify the potential risk factors contributing to the COVID-19 incidence rates at the district-level in Bangladesh. Spatial regression methods were applied in this study to fulfill the aim. Data related to 28 demographic, economic, built environment, health, and facilities related factors were collected from secondary sources and analyzed to explain the spatial variability of this disease incidence. Three global (ordinary least squares (OLS), spatial lag model (SLM), and spatial error model (SEM)) and one local (geographically weighted regression (GWR)) regression models were developed in this study. The results of the models identified four factors percentage of the urban population, monthly consumption, numbeapital city, Dhaka, to create self-sufficient regions throughout the country, especially in the north-western region.SARS-CoV-2 has triggered a major epidemic among people around the world, and it is the newest in the sequence to become prevalent among other infectious diseases. The drug repurposing concept has been utilized effectively for numerous viral infections. Considering the situation and the urgency, the idea of drug repurposing for coronavirus infection (COVID-19) is also being studied. The molecular docking method was used for the screening of 29 antiviral drugs against primary protease proteins (MPP) of SARS-CoV-2, spike ecto-domain, spike receptor binding domain, Nsp9 RNA binding protein, and HR2 domain. Among these drugs, in terms of least binding energy, Indinavir, Sorivudine, Cidofovir, and Darunavir showed minimum docking scores with all the key proteins. For ADMET (Absorption, Distribution, Metabolism