Bioactive glasses have attracted enormous attention in the field of biomaterials for dental and medical applications. Incorporation of antibacterial ions within BGs has been proved to be a promising approach to fortify their bactericidal character. In this study, homogenous BGs containing silver (Ag) ions were synthesized by sol-gel method. Subsequently, the presence of the embedded ions were characterized by X-ray fluorescence (XRF) elemental analysis and energy dispersive X-ray (EDX) spectroscopy. Moreover, released ions were measured in simulated body fluid (SBF) and their antibacterial effectiveness was further verified using minimum bactericidal concentration (MBC) and minimum inhibitory concentration (MIC) tests. A crystalline hydroxyapatite layer was formed on the Ag-BG surfaces at day 5 approved by X-ray diffraction indicating the preserved bioactivity. The resultant uniform, mono-dispersed and dense nanoparticles show 19 great potential for a range of orthopedic and dental applications.
  Chronic obstructive pulmonary disease (COPD) exacerbation and protective mechanical ventilation of acute respiratory distress syndrome (ARDS) patients induce hypercapnic respiratory acidosis.
 
  Extracorporeal carbon dioxide removal (ECCO
  R) aims to eliminate blood CO
  to fight against the adverse effects of hypercapnia and related acidosis. Hypercapnia has deleterious extrapulmonary consequences, particularly for the brain.  https://www.selleckchem.com/products/Nolvadex.html  In addition, in the lung, hypercapnia leads to lower pH, pulmonary vasoconstriction, increases in right ventricular afterload, acute cor pulmonale. Moreover, hypercapnic acidosis may further damage the lungs by increasing both nitric oxide production and inflammation and altering alveolar epithelial cells. During an exacerbation of COPD, relieving the native lungs of at least a portion of the CO
  could potentially reduce the patient's respiratory work, Instead of mechanically increasing alveolar ventilation with MV in an already hyperinflated lung to increase CO
  removal, the use of hypoxemia.
 In selected patients, ECCO2R may be a promising adjunctive therapeutic strategy for the management of patients with severe COPD exacerbation and for the establishment of protective or ultraprotective ventilation in patients with ARDS without prognosis-threatening hypoxemia.In order to explore a superior washcoat material to give full play to the catalytic activity of perovskite active components on the monolithic catalysts, three novel types of LaCoO3/washcoat/cordierite monolith catalysts were prepared by a facile two-step procedure which employed the cordierite honeycomb ceramic as the monolith substrate, the nano-oxides (ZrO2, ɤ-Al2O3, TiO2) as the washcoat, and the perovskite of LaCoO3 as the active components. The blank cordierite, powdered LaCoO3, semi-manufactured monolithic catalysts (washcoat/cordierite), and manufactured monolithic catalysts (LaCoO3/washcoat/cordierite) were characterized by XRD, SEM, XPS, N2 adsorption-desorption, H2-TPR, and ultrasonic test, and their catalytic activities and catalytic stability were evaluated by the toluene oxidation test. The research results indicate that the nanoparticles coated on the cordierite substrate as the washcoat can give full play to the catalytic ability of the LaCoO3 active components and also showed high catalytic stability. However, the catalytic properties of the monolithic catalysts vary notably with the species of nano-washcoat. Among all the catalysts, the porous honeycomb surface structure, uniform distribution, high ratio of surface adsorbed oxygen, and strong reducing ability together give the LaCoO3/ZrO2/cordierite monolithic catalyst the highest catalytic activity on the oxidation of toluene at low temperature, which could be attributed to the excellent interactions of perovskite and nano-ZrO2 washcoat. Therefore, the nano-oxides, especially the nano-ZrO2, have a broad practical application potential for toluene oxidation at low temperature as the washcoat of perovskite-based monolithic catalysts.In order to investigate concentrations, variability, sources, and human health risk of trace elements, 38 atmospheric dust samples were collected around Arak industrial area. The average concentrations of Cd~Zn, As, and Pb were 3.3, 2.5, and 2.4 times higher than the corresponding geochemical background, respectively, while concentrations of Co, Cu, Ni, and Hg were lower. Based on geo-accumulation index (Igeo), trace elements were classified between practically uncontaminated to moderate contaminated levels. The potential risk (RI) map showed that about 86% of the study area for all trace elements was in the moderate risk class. According to the results of positive matrix factorization (PMF) model, four factors were extracted for trace elements, including industrial sources, natural sources, mining, and transportation, that contributed about 30, 27, 26, and 17% to pollution of the area, respectively. The carcinogenic risks for inhalation exposure to Cd, As, Ni, and Co were lower than the permissible risk limit than the EPA recommend (10-6), indicating an acceptable level of risk. Results of the health risk evaluation indicated that the non-carcinogenic health risk (i.e., hazard quotient, HQ) for children and adults decrease following As > Pb > Ni > Zn > Cd > Cu > Co > Hg. When excluding As, the hazard index (HI) was lower than the safe level (HI less then 1) for all the trace elements, whereas HQ values of As for children and adults were 17.1 and 1.6, respectively, indicating a potential risk for children. In sum, several remedial actions to eliminate or to reduce the dust pollution are urgently required in the industrial area of Arak.Evidence revealed that climate change has a significant impact on grain production in China. Northeast China has abundant agricultural resources which can make the maximum contribution to national food security. This study examines the effects of climate variability and price anomalies on grain yield and land use in Northeast China. The analysis showed that different climate variability phase combinations based on Pacific Decadal Oscillation and North Atlantic Oscillation present variations in signals and different magnitude of effects over the study area. The results revealed that land use by total grain crop negatively responds to the increase in price anomalies in Heilongjiang and Jilin Provinces. To assess the impact of climate change on crop yield model, the yield models under dynamically downscaled regional climate models revealed that climate variables significantly contribute to total grain yields. In the near future, minimum temperature (- 0.26 °C under CanESM2-4.5, - 4.42 °C under HadGEM2-ES), maximum temperature (- 2.