https://www.selleckchem.com/products/prostaglandin-e2-cervidil.html 69, 95% CI 1.71-4.24), distant metastasis (OR = 10.35, 95% CI 1.01-106.24), poor tumor differentiation (OR = 1.78, 95% CI 1.03-3.09), increased depth of tumor invasion (OR = 2.72, 95% CI 1.73-4.30), advanced clinical stage (OR = 2.75, 95% CI 2.04-3.71), and recurrence (OR = 2.30, 95% CI 1.34-3.95). Furthermore, analysis results using Gene Expression Profiling Interactive Analysis (GEPIA) showed that the expression level of TRIM44 mRNA was higher in most tumor tissues than in the corresponding normal tissues, and the relationship between TRIM44 mRNA level and prognosis in various malignant tumors also explored in GEPIA and OS analysis webservers. Conclusions TRIM44 may serve as a valuable prognostic biomarker and a potential therapeutic target for patients with malignancies.Background High-intensity interval training (HIIT) has been shown to be more effective than moderate-intensity continuous training (MICT) for the physical rehabilitation. However, data on its suitability for older hospitalized patients is scarce. Methods Randomized controlled trial in a hospital setting. Inclusion of 100 patients, ≥65 years old, hospitalized for rehabilitation after an acute medical condition, in a two-week rehabilitation program of either four HIIT or three MICT sessions per week. Completion was defined as participation in all but two planned sessions accomplishing ≥50% of each session. We assessed upper-limb muscle strength (handgrip isometric strength test), lower-limb muscle strength (quadriceps and ankle flexion and extension tests); gait speed and spatio-temporal parameters (instrumented walkway), and exercise capacity (6-min walk test). All adverse events were recorded as safety endpoints. Results An intention-to-treat analysis showed a 44% completion rate for the HIIT group (95% CI, 30-59) and 77% for MICT (95% CI, 55-82). A modified intention-to-treat analysis restricted to patients who participated in ≥1