https://www.selleckchem.com/products/azd5991.html Conclusion Patients with CSVD change in the lateralization of attention compared with the normal elderly. The decrease in attention in patients with CSVD might be caused by the reduced ability of selecting useful information in the LH. Copyright © 2020 Cao, Zhang, Wang, Pan, Tian, Hu, Wei, Wang, Shi and Wang.Background The detection of large vessel occlusion (LVO) plays a critical role in the diagnosis and treatment of acute ischemic stroke (AIS). Identifying LVO in the pre-hospital setting or early stage of hospitalization would increase the patients' chance of receiving appropriate reperfusion therapy and thereby improve neurological recovery. Methods To enable rapid identification of LVO, we established an automated evaluation system based on all recorded AIS patients in Hong Kong Hospital Authority's hospitals in 2016. The 300 study samples were randomly selected based on a disproportionate sampling plan within the integrated electronic health record system, and then separated into a group of 200 patients for model training, and another group of 100 patients for model performance evaluation. The evaluation system contained three hierarchical models based on patients' demographic data, clinical data and non-contrast CT (NCCT) scans. The first two levels of modeling utilized structured demographic and clinical ge, this is the first study combining both structured clinical data with non-structured NCCT imaging data for the diagnosis of LVO in the acute setting, with superior performance compared to previously reported approaches. Our system is capable of automatically providing preliminary evaluations at different pre-hospital stages for potential AIS patients. Copyright © 2020 You, Tsang, Yu, Tsui, Woo, Lui and Leung.In recent years, deep learning (DL) has become more widespread in the fields of cognitive and clinical neuroimaging. Using deep neural network models to process neuroimaging data is an efficient method