https://www.selleckchem.com/products/ttk21.html RESULTS Of the enrolled 930 acute febrile illness patients, 801 (86%) were prescribed doxycycline or azithromycin and 725(78%) could be telephonically followed-up. Progression to acute encephalitis syndrome was seen in 6 of the 621 patients who received presumptive treatment, and 5 of the 124 who did not receive the treatment. The relative risk of developing acute encephalitis syndrome among acute febrile illness patients who were prescribed presumptive treatment with doxycycline or azithromycin was 0.20 (95% CI 0.06-0.65). The effectiveness of presumptive treatment with doxycycline or azithromycin strategy was 79.9% (95% CI 35.4-94). CONCLUSIONS Presumptive doxycline or azithromycin treatment to children presenting with fever in peripheral health facilities of the study blocks in Gorakhpur during August-November, 2018 was effective in preventing progression of acute febrile illness to acute encephalitis syndrome.OBJECTIVE To describe eye tumors in Indian children (age ≤ 21 years) presenting to a multi-tier ophthalmology hospital network in India. METHODS Hospital-record review. RESULTS During the 3-year study period (November, 2015 - October, 2018), 2911 children were diagnosed with 3003 eye tumors. The three most common benign tumors included conjunctival nevus (445, 22%), orbital dermoid cyst (206, 10%), and periocular infantile capillary hemangioma (181, 9%). The three most common malignant tumors included retinoblastoma (835, 88%), xeroderma pigmentosa related ocular surface squamous neoplasia (38, 4%), and rhabdomyosarcoma (17,2%). Based on the age group, retinoblastoma (n=834, 28%) was the most common tumor in all groups, except adolescence where conjunctival nevus (n=194, 21%) was the most common. CONCLUSIONS Overall, retinoblastoma is the most common tumor in children encountered in a referral based comprehensive ocular oncology practice in India.OBJECTIVE This network meta-analysis aimed at comparing the effi