https://www.selleckchem.com/products/inf195.html Cancer is a kind of disease which can be explained at the molecular level as triggered by accretion of damaged deoxyribonucleic acid. There are several genes involved in cancer, mainly belonging to two classes called tumour suppressors and oncogenes. Other than the well-known breast cancer susceptibility 1/2 genes, there are several other genes involved in the development of breast and ovarian cancers. However, since the past two decades the focus of research has been on and breast cancer susceptibility 1/2 genes. The current review was planned to delve into the structure and function of breast cancer susceptibility 1/2 genes to augment research on the genetics of breast cancer. The understanding of tumour suppressor genes is also helpful in the analysis of mutational spectra and to determine the treatment strategies in clinical interventional studies.Diabetes mellitus is a complex metabolic disorder which disrupts normal physiological functions of the body cells to take in and utilise glucose effectively. On the other hand, blood glycaemic control remains the primary therapeutic target for diabetic patients. Dietary starch is the main determinant of blood glucose. But dietary starch tolerance levels fluctuate between individuals, which might be due to difference in genetic variants of alpha-amylase enzyme. Additionally, genetic variability of cereal carbohydrates may also influence glucophenotype in terms of a specific glycaemic and biochemical derangement. Therefore, personalised carbohydrate/ starch based diets are needed to ensure optimum blood glycaemic control in diabetic subjects in prospective studies. To determine the competencies of charge nurses. The systematic review and thematic synthesis study was done at Iran from1 Apr 2018 to 31 Jul 2018. Five electronic bibliographic database (Science Direct, Pro Quest, Scopus, Pub-Med, Scientific Information Database) were systematically searched for relevant literat